6380 results
Our main goal is to clarify the behavioural and neurophysiological effects of short-term TUS on deep brain circuits in humans. We will compare the effects of Amygdala-TUS, dACC-TUS and sham-TUS to one-another using a behavioural task and fMRI. Our…
1. To identify the perceived barriers and facilitators for initiating and maintaining a healthy lifestyle in people with both DM2 and a low SEP. 2. To co-create a digital, personalised CBT lifestyle tool together with end users (people with DM2) to…
The objective of this study is to evaluate the insulin delivery of the Medtronic Implantable Insulin Pump System (MIIPS 2020).
To Identify genetic variants and clinical phenotypes associated with risk of HS and to characterize the key cellular and molecular mechanisms and pathways involved in the pathogenesis of moderate-to-severe HS.
The primary aim of the study is to assess the overall health of offspring born to a mother with solid organ transplantation, and to identify possible pre- and perinatal risks for diseases later in life. In addition, we would like to collect and…
We aim to define the growth trajectory of clonal hematopoësis after allogeneic transplantation, and identify potential modulating factors.
To generate a large, international Friedreich*s ataxia patient database (including healthy controls), alongside an integrated clinical and natural history database, which is linked to a biological samples and imaging repository, hereby creating a…
To develop a prediction model for EOCRC patients that estimates the risk of having low HRQoL one year after inclusion based on a comprehensive set of predictors including patient characteristics, disease and treatment factors, lifestyle variables…
to investigate the role of regulatory T cells in response to heat shock proteins in muscle and peripheral blood of patients with juvenile dermatomyositis. To identify patterns in T-cell responses and cytokineprofiles, in relation with clinical…
The current study describes the Antisocial High-Risk Cohort (i.e., WP3, a sub-project) of the larger Growing Up Together in Society Project (see appendix A), which has the aim to predict and understand behaviour that negatively affects society:…
The aim of this project is to unravel whether BPD after the neonatal period is a chronic inflammatory disease, and if markers of inflammation and/or oxidative stress are related to pulmonary morbidity in patients with BPD. Based on these findings,…
The primary objective is to examine the effect of twelve weeks supplementing daily one AstaPure® Oleoresin capsule on trans epidermal water loss (TEWL) in postmenopausal women. The secondary objectives are to investigate the effects on other skin,…
Primary Objective: Compare visual acuity between adults born prematurely and adults of general population born at full term.Secondary Objective(s): o Compare other anatomical and functional ocular outcomes (retina, macula thickness, refraction,…
To acquire metabolic health data from three dietary challenge meals for the development of an algorithm for personalised dietary advice, and subsequently test the effectiveness of this personalised dietary advice compared to a general healthy diet…
Our study aims to identify unique Metabotypes among individuals with overweight at risk of T2DM and assess their response to a 1-year precision dietary macronutrient modulation. The objective is to provide proof-of-concept that this approach…
In this proposal, we will collect samples from both US and international corneal ulcers, identify etiology, AMR, and local host immune response, and correlate with presentation and outcome.Specific Aim 1. Worldwide surveillance of organisms…
The objective of the Next Generation ImmunoDermatology project (funding NWO, program NWA-ORC) is to deep profile immune-mediated inflammatory diseases for the identification of biomarkers that can identify different disease endotypes that can…
To determine prevalence rates of H. pylori infection within gastroenterologists, gastroenterologists and endoscopy nurses (in training).
The primary objective is to evaluate the effectiveness of dietary nitrate in reducing muscle atrophy induced by bedrest. Secondary objectives include assessing its impact on insulin resistance, muscle strength, and cardiovascular function.…
Primary Objective: - Evaluate changes in immune response during oral immunotherapy with either peanut or baked milk in children with a mild peanut or cow*s milk allergySecondary Objective: - Compare the immunological changes at baseline and over…