11 results
to investigate the analgesic effect of high frequency 10 Hz rTMS on experimental pain measured through quantitative sensory testing (QST) in healthy subjects.
The primary aim of this project is to discover new cellular (non-invasive) biomarkers for the diagnosis and monitoring of immune-mediated liver diseases. Secondly we aim to effectively differentiate AIH from DILI and NAFL from NASH.
In this study, we want to assess the variability and the causality between hormonal changes and aggressive behaviour within a psychotic patient, an anti-social personality disordered patient, an anti-social personality disordered patient with a PCL-…
The purpose of the sub-study is to do research into markers which will hopefully assist to diagnose the condition Peripartum Cardiomyopathy as early as possible. The blood donated for research will also assist in the assessment of women having a…
This study will investigate a comparison group of women treated with a conventional (non-nerve sparing) RHL for cervical cancer (CC) at the Academic Medical Centre (AMC). Together with the data collected of women treated with a nerve sparing radical…
• To determine the immunogenicity prediction in PBMCs of patients treated with Infliximab and Adalimumab using the MAPPs assay.• To investigate whether the peptides presented upon in vitro loading of Dendritic Cells are also presented in vivo after…
This study will investigate the value of C. burnetii-specific whole-blood IFNγ and IL-2 production assays in QFS patients that have either recovered, or are still substantially fatigued. This will show us if these assays can serve as potential…
We aim to proof that introduction of (rapid) NGS-based sequencing (WES/WGS) as a first tier genetic test in the diagnostic process for critically ill newborns admitted at the NICU and patients with severe neurodevelopmental disorders leads to faster…
Determine the relationship between stratum corneum lipids (and their enzymes) and inflammatory markers in patients with AE. This is achieved by measuring:i) The SC lipid matrix and bound lipids, focussing on ceramides and its biosynthesis (i.e. the…
We aim to study the role of PVAT in regulation of vascular function, tissue perfusion and glucose uptake in muscle. We hypothesize that PVAT determines insulin-induced vasoreactivity when studied ex vivo and correlates with insulin-induced…
Primary ObjectiveThis proposal concerns the inclusion of a peripheral quantitative computed tomography (pQCT) device in the Rotterdam Study to perform osteoporosis etiological research. Since 1990, the Rotterdam Study has performed research in the…