27 results
The different processing of formulas will have an effect on stool characteristics such as consistency, frequency, amount and colour.
The aim of our descriptive study was to quantify the disease burden leading to hospital-based care, repatriation or death in Dutch travelers during their stay in a foreign country, including Europe. The outcome of this study could be used as…
We aim to identify immunological parameters during (immune)therapy. We will study the effect of (immune)therapy on generic immune mediators and more specifically for NK cell, T effector and Treg cell functionality. Furthermore, we will explore DNX…
With the extended LAST STRONG Study, we aim to (1) collect 3-year and 5-year natural history data, (2) implement the natural history data collection into clinical care and international guidelines (reach trial readiness), and (3) do in-depth…
To investigate the role of talkers* voices in speech communication in NH, HI, and CI children and adult listeners, and how the perception of talker voice information relates to the processing of indexical and linguistic information among these…
The goal of this study is first to test the effectiveness of a short-term, attachment-based parenting intervention (NIKA) for victimized mothers and their children after domestic violence (phase 1). Next, we will evaluate the additional…
To determine the burden of disease due to RSV in young term born infants.The active cohort study is expanded to other family members during the COVID-19 pandemic to gain insight in COVID-19 related burden to families. In addition we would like to…
The aim of the Survey is to better understand the variability and progression of Pompe disease and to continue to monitor and evaluate the long-term effects of available treatment options and support measures including ERT with alglucosidase alpha…
To assess achieved immunity against COVID-19 across the different age groups in The Netherlands by testing a representative part of the Dutch population for the presence of SARS-Cov-2 specific antibodies in serum
Assessing the feasibility of the research procedures, the burden on participants, the degree of dropout and reason, the interest in participating.What is the main treatment effect for parents / carers motivating them to participate in this study?•…
The aim of the study is to collect video recordings which will be used retrospectively internally at Philips to test whether an algorithm can be used to measure the behavior and physiology of babies by using a camera and/or wearable. Development of…
Primary:Evaluate the impact of SoC anemia management on Hgb concentrationsSecondary:- Characterize the use of ESA therapies in management of anemia associated with moderate to severe CKD in children and adolescents aged <18 years- Evaluate…
Clinical feasibility of the urine collection device, indicated by staff and parents.
Primary Objective: Prenatal and postnatal growth trajectories and prenatal maternale exposures, type of feeding, appetite regulating hormones and (epi)genetic factors in association with body composition at ages 1,3, 6 and 9 months and 1 year, 18…
Primary objective• To characterise natural disease progression rates of MRI- and/or US-assessed measures of muscle properties and muscle function and strength tests in children with neuromuscular disorders through standardized annual follow-up…
To characterize the natural history of exocrine pancreatic function as measured by FE-1 in infants with CF <12 months of age
The aim of SPIRIT is to investigate the mechanisms of the immunological tolerance to FVIII in patients with hemophilia A aged younger than 18 years using NFT for prophylaxis.
The overarching objective of this master protocol is to study the risk factors (personal, clinical and lifestyle factors) for-, and consequences of- , changes of nutritional status (both over- and undernutrition) in children with cancer. Based on…
In this study, we to confirm the cuff design and make sure it works. Aspects such as safety and ease of use are also evaluated.
To assess the pharmacokinetics of various cytotoxic agents (carboplatin, cisplatin, cytarabine, dactinomycin, daunorubicin, dinutuximab bèta, doxorubicin, etoposide, methotrexate, vincristine or thiotepa) and kinase inhibitors (ALK, RAS pathway,…