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Abnormal sex hormone exposure of the brain; possible neuroendocrine implications for cognition in adult transsexuals and women with polycystic ovarian syndrome as clinical models

The overall aim of the present work is to evaluate the individual role of androgens and estrogens on brain function in the human with a focus on cognition. Both clinical models give us the opportunity to evaluate cognitive functions and brain…

The effect of exenatide compared to insulin glargine on cardiac function and metabolism in type 2 diabetic patients with congestive heart failure: a randomized-controlled trial

In this study we will assess the effects of exenatide on cardiac metabolism and function in patients with T2DM and CHF. We will address the following hypothesis: exenatide improves global cardiac function in CHF patients with T2DM, by favorable…

Trauma-memories, Stress and Craving in Substance Abuse Patients with a Traumatic History.

Do trauma cues trigger more craving in individuals with substance dependency and PTSD in comparison with substance dependent individuals without PTSD? If so, is this effect trauma-specific or are SUD-patients with PTSD more sensitive to general…