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The effect of collagen supplementation on human tendon protein synthesis

The main objective of the current study is to assess the impact of dietary collagen supplementation on human tendon protein synthesis.

Non-invasive fetal electrocardiography and speckle tracking echocardiography in the second trimester, 16 until 28 weeks gestational age: a prospective cohort study.

The primary objective of this study is to generate reference values for NFMS parameters as well as for 2D-STE parameters during the second trimester, 16 until 28 weeks gestational age. The secondary objective is to investigate the diagnostic…

The effectiveness of Cerclage for the reduction of extreme preterm birth and
perinatal mortality in Twin pregnancies with a short cervix.

To assess the effectiveness of a cerclage in women with a twin pregnancy with a midpregnancy short cervix compared to standard treatment (no cerclage) in the prevention of extreme preterm birth (PTB) < 28 weeks of GA.

COMPRehensive assessment of prevalence, risk factors and mechanisms of impaired medical and psychosocial health outcomes among Adolescents and Young Adults with cancer: the prospective observational COMPRAYA cohort study

To examine the prevalence, risk factors and mechanisms of impaired health outcomes (short- and long-term medical and psychosocial effects and late effects) over time among a population-based sample of AYA cancer patients.Primary Objective: - To…

HASTA study - Healthy Aging starts with a healthy STArt;Remote electrophysiological cardiotocography (eCTG), evaluation of feasibility in (a selected group of) complicated pregnancies from 32 until 37 weeks gestational age in a Home@Hospital setting: a prospective cohort study

To evaluate the feasibility of remote eCTG monitoring in complicated pregnancies between 32-37 weeks in a Home@Hospital setting. Secondary objectives are to evaluate automated interpretation of remote eCTG monitoring and to assess perinatal and…

Study on the effect of biperiden and donepezil on attention and memory in healthy elderly people

Primary objective• Assess the ability of donepezil to reverse biperiden-induced effects on adaptive tracking performance at timepoint 4h Secondary objectives• Evaluate the PK of donepezil and biperiden• Investigation of pro-cholinergic effects of…

The prospective data collection initiative on on small bowel, colorectal and anal cancer - a prospective observational cohort study.

The main objectives of this project are:- To start a prospective observational cohort study of patients who have been diagnosed with CRC, small bowel and anal cancer and follow them from time of diagnosis until death.- To prospectively collect data…

An exploratory, multi-centre, two-part study to describe chronic induced urticaria characteristics and explore novel biomarkers with a multimodal patient profiling approach by comparing CIndU patients to chronic spontaneous urticaria patients and healthy volunteers

The objective of this study is to deep phenotype CIndU (subtype SD and ColdU) and detect novel biomarkers for diagnosis and treatment response as well as establish methodologies for (non-) invasive monitoring of treatment effects in chronic…

Research into the suitability of the NeuroKit test method in measuring drug effects

Primary Objectives: Quantify the PD effects of CNS active compounds with distinct mechanisms of action (lorazepam, modafinil and S-ketamine) with NeuroKit and NeuroCart in healthy male and female participants.   Estimate the…