142 results
A Cross-sectional Study of Renal Function in Treatment-naïve, Young Male Patients with Fabry Disease
The objectives of this study are (1) to document renal function and other Fabry disease manifestations across age in treatment-naïve, young male patients with Fabry disease; and (2) to provide a reference group for comparison with interventional…
Objective(s): The primary objective of this study is to asses the dynamic vaginal pressure profile in two groups: 1) women diagnosed with dyspareunia and, 2) women with primary vaginismus. The secondary goal is to assess vaginal reflexes in women…
to compare in vivo total kidney 123I-MIBG uptake (by counts per pixel) by 123I-MIBG scintigraphy to direct ex vivo 123I-MIBG uptake of the flushed kidney as directly assessed with phosphor imaging.
The aim of the study is to investigate the effects on time trial / cycle test performance after ingestion of Snelle Jelle 'kruidkoek' and water, banana and water, or only water.
The objective of this study is to evaluate the differences in exercise performance in healthy subjects, caused by the open-ended (CWR) en closed-ended (TT) character of the exercise test when cycled at the same absolute work rate. In addition, the…
In this study we want to quantify the contribution of the efference copy in the difference between active action and passive action using somatosneory evoked potentials (SEP).Our first hypothesis is that during the motor planning stage, the…
To evaluate exhaled breath sampling approaches and their impact on results quality. To establish if sampling procedures impact specificity and sensitivity in extracting information of interest * in our case impact of garlic/fish oil supplements on…
The main objective of this study is to investigate the predictability of persisting post-surgical pain (PPSP) after TKA using electrical quantitative sensory testing (eQST) and nociceptive perception thresholds (NPT) in combination with a pre-…
Primary Objective: To investigate the clinical symptoms including pain response after third molar (i.e. wisdom teeth, or short: M3) extraction in relation to biomarkers and preoperative pain profile of individual subjects Secondary Objective: To…
To elucidate the changes in the timing of sleep and waking in different chronotypes (e.g. *owls* vs. *larks*) with at least 2 hours of social jetlag exposed to short wavelength (blue) light in the mornings upon awakening using Philips goLITE blu…
The objective of the study is to analyse flow pattern, especially individual variation, and the extend of voiding symtoms in young females and
The proposed intervention aims to increase sport participation of youth with behavioural and/or learning problems as part of their youth care program within a Rotterdam youth care organisation. This will allow us 1.) to empirically test the effect…
Evaluate the effect of menarche and menstrual cycle on the QTc interval among girls with genetically-confirmed mutations causing LQTS type 1 (LQT1) and type 2 (LQT2).
To study the influence of systemic blood flow and mean arterial pressure on cerebral blood flow in patients undergoing on-pump cardiac surgery.
The current study evaluates the OrthoSensor and investigates whether the combination of the Vanguard® Knee System with the OrthoSensor results in a faster recovery and better clinical outcomes during short follow up compared to conventional TKA (…
Investigating the neural mechanisms underlying the anticipation of food reward induced by visual cues related to different foodcharacteristics in healthy males would provide 1) brain activity patterns that can be associated with the anticipation of…
This study aims to identify global and local determinants of HPV vaccine acceptability, HPV vaccine uptake and compliance as well as identify logistics and programmatic issues in each country to offer the HPV vaccine, as a potential cervical cancer…
Primary Objective: To compare the function and strength of the hip of patients with a trochanteric fracture with and without a fracture of the lesser trochanter.Secondary Objective(s):The following parameters will be assessed and compared for…
To investigate the direct role of local beta oscillatory activity in the frontal cortex during a reversal learning paradigm.
The current study is part of a larger project that aims at identifying genetic profiles that render subject vulnerable to pronounced memory decline at old age. This part of the project will assess cognitive functions in three different age cohorts…