1600 results
Anastomotic strictures are common after esophageal resection. These strictures often need multiple dilation procedures with Savary bougies, and some even fail despite many dilations. Based on the literature and our pilot study of electrocautery…
To compare the immunogenicity of the whole cell versus the acellular pertussis component of the DTP IPV-Hib vaccine as measured by the antibody titers at 11 months before the 4th vaccination and at 12 months.
Findings from both epidemiological and basic research point to the possibility that NSAIDS impede the deterioration in schizophrenia.
Affective disorders (i.e. depressive or anxiety disorders) of dementia caregivers are largely preventable.
Routine risk assessment and care evaluation reduces the frequency of violent behaviour (primary outcome) in outpatient forensic psychiatric clients, and increases the quality of life, psychiatric and social functioning, and satisfaction with care of…
Assembly of a large sample of patients/families with nonsyndromic oro-facial clefts from Central Europe for identification of genetic factors responsible for this phenotype by usage of association and linkage disequilibrium studies.
Primary aim: to investigate the possible existence of *transient* or non-progressive non-atherosclerotic arteriopathy as a cause of AIS in young adults, and to describe the course of young adulthood unilateral intracranial arterial disease.Secondary…
To obtain comprehension in the development of quality of life during and after clinical rehabilitation and the factors that influence it. This leads to the following questions:Primary questions(1) What is the progress of mental health and well-being…
1. Is passive movement therapy an effective intervention on the severity of paratonia in comparison with usual care without passive movement therapy?2. Is passive movement therapy an effective intervention for improvement of daily care?
To establish one large overarching cohort including all types of SpA (both non-radiographic, radiographic axial SpA and peripheral SpA) regardless of the disease stage and treatment and to longitudinally asses several disease aspects of SpA. The…
Main objectives: To obtain true population-based prevalence and incidence figures, as well as insight in the natural history of PSC and PBC in The Netherlands.Secondary objectives: to determine risk factors correlated with PSC and PBC respectively,…
Primary* To compare the efficacy (Major Molecular Response, MMR, rate at 12 months) Secondary* To compare the rate of durable MMR at 24 months in patients with a MMR at 12 months* To compare the rate, time to and duration of complete cytogenetic…
Primary objective· • To investigate the safety and tolerability and establish either the dose of KU-0059436 which causes inhibition of PARP in combination with an active dose of carboplatin or the maximum tolerated dose (MTD) of KU-0059436 in…
To evaluate the cost-effectiveness of the Demands and Capacities Model based treatment (Dutch standard) compared to the Lidcombe programme for early stuttering intervention.Follow-up: Long-term outcome, taking into account recent genetic findings.
To study the presence, number, type and specificity of tumour-specific immune response in the peripheral blood, tumour-draining lymph nodes and the tumour of patients with different types of HNSCC at different time-points during their normal…
To evaluate the efficacy ofa. early intensification of rituximab combined with 2-weekly CHOP+G-CSF (R-CHOP14) in remission induction treatment in comparison to standard R-CHOP14b. maintenance treatment with rituximab in patients in remission after R…
This study has been transitioned to CTIS with ID 2024-518269-92-00 check the CTIS register for the current data. The objective of the study is to gather more information about the long-term effect of enzyme therapy in patients with Pompe disease…
The objective of this study is to assess the clinical presentation, the treatment and the complications of treatment in moderate and severe von Willebrand disease. Another goal is to investigate the influence of von Willebrand disease on quality of…
In addition to the aforementioned passive monitoring of high-risk persons with respiratory complaints after exposure to HPAI, this project aims to set up active monitoring (exclusion diagnosis) in high-risk persons without respiratory complaints in…
Identification of type 2 diabetes susceptibility genes in the Duch population.