2170 results
Primary objective of this study is to evaluate the clinical effect of a long term treatment (8 weeks) with oral B2-agonists in CF patients with residual CFTR function, especially on lung function (spirometry and airway resistance). Secondary…
Primary Objective Our primary aim is to evaluate the course of cognitive functioning (stability, impairment or decline, or improvement as compared to Dutch controls) after usual care SRS in patients with 1-10 BM at time of treatment initiation.…
To evaluate the safety and efficacy of abicipar (2 mg), compared to 0.5 mg ranibizumab in treatment-naïve patients with neovascular AMD.
This study is designed to evaluate the effectiveness and safety of the MID-C System.
To evaluate the safety and efficacy in terms of progression-free survival (PFS) and overall survival (OS) of nintedanib + pemetrexed / cisplatin followed by nintedanib versus placebo + pemetrexed / cisplatin followed by placebo as first line…
The purpose of the study is to compare LA-EP2006 and Neulasta® with respect to how quickly and to what extent the compounds are absorbed and eliminated from the body after injection under the skin of the abdomen (this is called pharmacokinetics). It…
Primary Objective: -To explore the percentage of positive total PEth levels in blood, as a proxy of alcohol consumption, in pregnant women during their first visit to the obstetrics department.Secondary Objectives: To explore the distribution of…
To assess the efficacy of different orthopaedic footwear concepts on the plantar pressure and patients satisfaction in diabetic patients at risk for foot ulceration
To provide further insight into Souvenaid*s hypothesised mode of action, the current NL-ENIGMA study explores brain glucose metabolism in mild cognitive impairment (MCI) and mild dementia due to AD, using Positron Emission Tomography with 18F-FDG-…
To determine the true prevalence of pneumonia in exacerbating COPD patients by low-dose CT
Empathy is related to quality of life, depression, insight and social functioning and may be an important factor in recovery of people with schizophrenia. Empathy is impaired in schizophrenia, however it is not clear which elements of empathy are…
The proposed study will test whether the intervention-based parenting assessment of the parents* capacity to improve (VIPP-APP; Video-Feedback intervention to promote Positive Parenting for the Assessment of Parenting Potential) contributes to…
Primary objective of this study is to improve identification of epileptic HFOs in EEG and MEG, by comparing them to HFOs in corticography. Secondary objectives are to study the predictive value of non-invasively recorded HFOs for disease activity…
To determine the tacrolimus bioavailability after tacrolimus administration via a rectiole.
To determine and compare PK profiles of two of the most used ROOs in cancer patients: one intranasal fentanyl formulation (INFC, Instanyl®) and one sublingual fentanyl formulation (SLF, Abstral®).
Primary objectives: 1. To translate and adapt the iCBT program TELLUS for use in IFRC humanitarian aid workers2. To determine feasibility of TELLUS in terms of: completion rates and self-reported treatment credibility/ expectancySecondary objective:…
The primary objective of this investigation is to assess the performance of the ANSeR Software System by quantifying and comparing the diagnostic accuracy of investigation personnel using the ANSeR Software System with the diagnostic accuracy of…
The purpose of this study is to investigate the relation between scapular movement, muscle activation and cranial translation in healthy volunteers.
Compare the clinical- and cost-effectiveness of blended cognitive behavioral treatment (bCBT) to treatment as usual (TAU) for adults with MDD in specialised ambulatory mental healthcare.
Primary Objective:To describe the total apparent CYP3A mediated clearance (Cl/F) of midazolam in the paediatric intensive care population from the age of 0 to 6 years, as surrogate marker of intestinal and hepatic CYP3A activity.Secondary Objectives…