2170 results
This study aims to determine whether the ILC populations differ in the lungs of different phenotypes of asthmatic patients and healthy subjects and how these cells are regulated by bronchial epithelial cells. Furthermore we want to study how this is…
Primary Objective: Evaluate the functional integrity of the nociceptive system after percutaneous cervical chordotomy using Laser Evoked Potentials Secondary Objective(s): change in opioid consumption after percutaneous cervical chordotomy using a…
To investigate the diagnostic accuracy of subtractionless first-pass single contrast medium dose (0.1 mmol/kg) peripheral magnetic resonance angiography (MRA) using two-point mDixon fat suppression in comparison to the established standard of…
Primary Objectives: 1. To assess the values of ARI and APDR in NICM patients. 2. To assess the three-dimensional heterogeneity of ARI and APDR in NICM patients.3. To compare 1. and 2. with the same data collected from non-NICM patients.4. To…
This study aims to improve the first phase of rehabilitation after THA. The primary objective is to analyse the effect of feedback to the patients. The secondary objective is to quantify the weight bearing in the early phase after THA surgery.
To identify molecular alterations associated with cervical tumorigenesis, that could be used as biomarker for improving detection and differentiation between cervical cancer, cervical intraepithelial neoplasia and normal cervical tissue.
Within a clinical population of multi-problem families a study will be conducted to the quality of the therapeutic relationship, the perception of the family on this relationship and the role of attachment representations of therapists and treatment…
The main objective of this study is to evaluate which urine collection method for non-toilet trained children is most suitable for exposure measurement to pesticides with respect tothe burden and convenience, including ease of use, for infants and…
Primary objective: Is their a difference in gait pattern between patiens with a resurfacing hip arthroplasty compared to a total hip arthroplasty after 5years?
Objective: To determine whether serum concentration guided dosing of infliximab is not inferior to standard dosing based on bodyweight in patients with severe sarcoidosis in terms of FVC change at 26 weeks.
The purpose of the MILESTONE validation study is to validate low burden, reliable and efficient bespoke MILESTONE measures related to transition from CAMHS to AMHS. The primary objective is to validate the MILESTONE Suite of Instruments: a. The…
The objective of this study is twofold.One aim of the study is to investigate the effects of tDCS (anodal, cathodal and sham) on balance correcting responses and simple reaction times in lower extremity muscles. We will determine whether the effects…
In our laboratory we are able to characterize and culture MSCs. In order to study more extensively the possible alterations in MSC biology in AA we will investigate bone marrow cells of patients with newly diagnosed AA and at the time of response…
Investigating the neural mechanisms underlying the anticipation of food reward induced by visual cues related to different food characteristics in healthy adults would provide 1) brain activity patterns that can be associated with the anticipation…
Primary: To evaluate the effect of MBX-8025 on LDL-C.Secondary: To evaluate the effects of MBX-8025 on other lipid parametersTo evaluate the safety and tolerability of MBX-8025.To evaluate steady-state trough plasma levels of MBX-8025 and its…
Primary objectives* 18F-FLT-PET/CT: - To correlate the percentage change in SUV between baseline (SUV-1) and early therapy (SUV-2) with pathological quantification (% of viable tumor cells) of the primary tumor after pre-operative chemotherapy in…
To study the macro- and microcirculatory effects of VV-ECMO treatment.
Main objectives: This exploratory intervention study is set out to examine effects of tailor-made lifestyle advice, based on observed individual temporal patterns of lifestyle factors and experienced pleasure, as a non-pharmacological means to…
The study is intended to (1) confirm the reduced x-ray shadow of the MicroTEE (S8-3t) probe, and to asses whether this results in a more delayed first pull back or a reduction in the number of pull backs or not; and (2) to evaluate the feasibility…
To investigate if norepinephrine is safe and effective in increasing blood pressure and systemic blood flow in premature and full-term neonates with shock and/or hypotension.