2170 results
The primary objective of the study is to explore and compare the signal strength of different probes for measuring pulse oximetry signals on different body locations. The secondary objective of the study is comparing aspects of user experience (via…
The present study is designed 1) to compare the long-term survival using the recurrence rate of hallux valgus in the scarf and chevron osteotomy group; 2) to compare the long-term results with the results at 27 months; and 3) to asses patients* view…
Primary Objective• To explore the pharmacodynamic effects of topically applied omiganan • To explore the treatment effect of omiganan compared to placebo in uVIN patients Secondary Objectives• To assess safety and tolerability • To explore the…
To identify biomarkers associated with OSA in bariatric surgery patients prior to surgery; to investigate the effect of bariatric surgery on these with OSA associated biomarkers; to identify biomarkers that predict amelioration of OSA after…
The purpose of this study is to research the influence of vibration on the neck muscles on JPE and the effect of aging on this parameter in patients with a-specific neck pain. The second purpose is to research the influence of vibration on the neck…
The purpose of this prospective post market observational pilot study is to evaluate the effect of DRG stimulation in the management of chronic discogenic pain in subjects who are refractory to other available treatments. Selected subjects will not…
The current research proposal intends to study the therapeutic potential of moderate intermittent hypoxia (IH) exposure in subjects at high risk of developing type 2 diabetes, and aims to address the following key objectives:1) To investigate the…
Primary Objective: To study whether nocturnal symptoms of CTS depend on wrist position and, if so, on which position. Identifying which wrist position aggravates CTS could help design a more effective splint. Secondary Objective: To study whether…
Primary objectiveTo evaluate the change in quality of life (NEI VFQ 25) in subjects with DME during the first year of treatment with aflibercept according to the EU label for DMESecondary objectives• To assess further the safety and tolerability of…
Objective: The primary objective of the study is to determine the effect of standard treatment with levothyroxine in TR*1 deficiency on:- Neutrophil and macrophage function- Erythropoiesis- Thyroid hormone target gene expression- Plasma metabolome
To determine the efficacy of quantification of vitreous floaters captured by SLO-imaging technique for Nd:YAG vitreolysis for persisting vitreous floaters.
Will spinal anaesthesia with sufentanil and bupivacaine heavy cause less hypotension compared to bupivacaine heavy alone? Will there be less use of ephedrine/fenylefrine/noradrenaline if sufentanil is added to bupivacaine heavy for spinal…
The purpose of the study is to investigate how quickly and to what extent JNJ-63623872 is absorbed, distributed, metabolized (broken down) and eliminated from the body (this is called pharmacokinetics). The compound to be administered will be…
The study is designed to evaluate the possible association between genetic variants and susceptibility to IRF, based on previous studies in autoimmune-inflammatory diseases (celiac disease, type 1 diabetes and rheumatoid arthritis).
In the current study we aim to assess the energy requirements and physical activity patterns in professional soccer players along with their nutritional intake patterns. As such, this study will provide valuable information to optimize the…
We aim to recognise potential genetic modifiers for mutations in PMS2. This will be approached through comparing a selection of CRC-related genes in the exome of members of a PMS2 family who differ in age of onset and severity of disease.
The primary objective is to establish, in healthy subjects, the time-dependent effects of social stress on the tendency to generalize neural, emotional and fearful memories to new contexts. The secondary objective is to assess whether several…
Primary, this study investigates the effect of VR on procedural pain. Secondary, this study investigates the effect of VR on satisfaction with the procedure, identifies patient-related, burn wound-related and psychology-related variables associated…
Primary objective:Plasma levels of clonidine, in order to describe pharmacokinetic and pharmacodynamic properties of intravenous clonidine in critically ill ventilated ICU patients.Secondary objectives are: * to evaluate the effect of a 3-hr loading…
This study is not intended to improve your health, but is necessary for the further development of RO7034067 .The study will be performed in 3 parts, Parts 1, 2 and 3. This document only refers to Part 1/2/3 of the study . Part 1:A single dose will…