2170 results
Primary goal: mean linear wear of the cross-linked polyethylene F.A.L. cup compared to the mean linear wear of the standard polyethylene F.A.L. cup at 5 years postoperatively. Secondary goals:1. mean linear wear (millimeters/year) at 1 year, 3 years…
The primary objective of our study is to investigate the performance of FCH-PET as a second-line imaging modality for localizing hyper-functioning parathyroid gland(s) in patients with biochemically proven PHP for whom surgery is indicated, thereby…
• To assess the prevalence of short stature, in combination with an aberrant IGF-1 in combination with IGF-BP3 in the entire cohort of childhood cancer survivors and the therapy related risk factors.• To assess the distribution of IGF-1 and IGF-BP3…
The aim of this study is to assess the prognostic value of sarcopenia and geriatric markers for survival and treatment tolerability and fluctuation of this value between several oncologic conditions. Secondly, we focus on the value of repeated CGA…
The main objective of the study is to investigate the muscarinic cholinergic system as a biological substrate for cognitive dysfunction in first episode psychosis patients, i.e. at onset of illness. We seek to assess whether deficits in M1…
Determine the repeatability, inter and intra-observer variability of the *Scolibed*. Determine the variation in stiffness for healthy individuals and for scoliotic patients. Compare the results of healthy individuals and scoliotic patients.
The goal is to find answer to the question: do epidural injections with corticosteroids in patients with sciatica have a positive effect on pain, absenteeism from work and number of operations compared to standard care (pain medication only).
To assess whether treatment with DBS can reduce or resolve TDD and if DBS can induce beneficial or side effects in particular psychiatric and or cognitive symptoms.
The main objective of this prospective randomized study is to examine the effect of low-dose radiotherapy on pain sensation in patients with early OA of the hip. Our hypothesis is that radiotherapy can achieve a pain-reducing effect of at least 20%…
The main objective of the current study is to evaluate which patients in the twilight zone of PH will benefit from PAH specific therapy. We will assess the (early) response to PAH specific treatment and determine potential predictors of adverse…
The objective is to estimate the association between biomarkers of myocardial injury and myocardial infarction in patients undergoing cardiac surgery. Myocardial infarction will be established with both a new and very early marker of myocardial…
The relative effects of sildenafil on mortality when administered at the three doses indicated above in adults with PAH will be evaluated in this clinical study. In addition, the relative effects on clinical worsening and 6-minute walking distance (…
This study had two objectives:1. which factors determine outcome of treatment of children with functional childhood constipation referred to the outpatient clinic of multidisciplinary treatment clinics in the Netherlands;2. which factors can be…
Primary Objective: To assess whether the combination of Saline Infusion Sonohysterography (SIS) and Endometrial Brush Biopsy (EMB) will create an innovative algorithm for diagnosing corpus uteri malignancy in postmenopausal women suffering from…
The primary study objective is to assess the proportion of patients who remain within the IGF-I age adjusted normal limits with pasireotide LAR (60 mg) monotherapy, after 24 weeks of treatment.Secondary study objectives are assessment of the…
(i) identification and cellular characteristics of red blood cells from patients with altered ion homeostasis and delivery of novel and easy-to-use diagnostics for rare anemia*s, for patients with: a) a known primary defect in the ion channels of…
The study will collect data related to symptoms of recurrent biliary stent obstruction requiring reintervention, adverse events, and a variety of important secondary endpoints including technical success and time to symptomatic recurrent biliary…
Primary:2. To investigate the prevalence of vulnerable plaques, i.e. plaques with intraplaque hemorrhage on MRI, in individuals with type 2 diabetes, impaired and normal glucose tolerance and a minimal plaque thickness of 2mm on ultrasonography. To…
To compare the efficacy of alitretinoin and azathioprine in the treatment of severe chronic non-hyperkeratotic hand eczema.
The aim of our pilot intervention study is 1) to describe the effects of lactic acid-containing vaginal douching on the vaginal microbiota dynamics using novel molecular laboratory methods.2) to describe the effect of lactic acid-containing vaginal…