2170 results
To study the neurological changes that explains the recovering of visual field defects after visual restoration therapy.
The main objective is to assess target attainment of cefotaxime levels in the critically ill treated with either continuously or intermittently dosed cefotaxime. Secondary objectives are: to develop a predictive mathematical pharmacokinetic (PK)…
The aim of the current study is evaluation of the Certe A/C service system. This is achieved via 2 workpackages:Workpackage 1 constitutes of describing patient characteristics (age, gender, current medication, smoking status and comorbidities) of…
PrimaryTo assess the efficacy of LEE011 compared to placebo in patients with relapsed/refractory teratoma with recent progressionSecondaryTo assess other measures of efficacy of LEE011 compared with placebo To assess safety and tolerability of…
To examine the motor cortical control of antagonist muscle function in younger and older adults
To identify predictors for the different treatment options for obesity (1. combined lifestyl intervention plus, 2. E-health treatment, 3. bariatric surgery; inclusion for treatment options 1 and 2 takes place in the EMC, inclusion for the treatment…
To test the suitability of OCT for in vivo imaging of the vascularisation and surrounding tissue of burn wounds and scars.
In this study, we aim to test the feasibilty, reliability and validity of the MOX-accelerometer in measuring daily physical activity in children with mitochondrial disease.
Physical functioning at the workplace in patients after total knee arthroplasty: a feasibility study
The primary aim of this pilot study is to demonstrate the feasibility of measuring physical functioning at the workplace among TKA patients and healthy colleagues objectively. Secondly, to get a first impression of objective physical functioning of…
The primary objective of this trial is to assess the effectiveness of IG-SBRT in patients with medically inoperable early stage, centrally located NSCLC and in those who are not willing to undergo surgical treatment.The primary measure of…
The purpose of this study is to test whether perceptual expectations modulate V1 activity consistent with *hypo-priors* in autistic individuals.
The main objective of this study is to investigate the predictability of persisting post-surgical pain (PPSP) after TKA using electrical quantitative sensory testing (eQST) and nociceptive perception thresholds (NPT) in combination with a pre-…
To investigate the effect of tourniquet application on the coagulation system in patients undergoing a knee arthroscopy. A finding of more prominent activation of the coagulation system with tourniquet use than with non-use will create an important…
1. Determine the relationship between periodontitis and HIV-related immune activation and hypercoagulability.2. Explore the role of oral microbiota as effect modificator of the relationship between periodontitis and immune activation in HIV-infected…
Primary objectives:- To investigate the long-term outcome after successful treatment (no subretinal fluid on OCT) in the PLACE trial.- To investigate whether a cross-over treatment of half-dose PDT to HSML in cCSC patients who either did not respond…
Primary Objective: The painscores regarding abdominal pain among women with primary outflow obstruction in comparison with an age matched control group.Secondary Objective(s): The prevalence of sexual problems due to the congenital anomalies or the…
To investigate the feasibility and efficacy, expressed as percentage funcitoning time and time in target range, respectively, of an automated closed-loop glucose control system based on subcutaneous continuous glucose measurements in critically ill…
To validate the use of single urethral sensor catheter in demonstrating urethral pressure variations during filling cystometryIncidence of significant urethral pressure variations during urodynamic filling phase measured with three urethral sensor…
This study aims to investigate the effect of switching from Atripla® to Eviplera® on neurocognitive performances (neurocognitive testing) and imaging (functional MRI scanning) in virologically suppressed HIV-infected patients and stable on atripla.
Objective: Primary objective is to demonstrate non-inferiority of the e-prescription to the use of antidepressants on the short term. Secondary objectives are to assess its effect on long term outcomes, antidepressant use, and to assess its…