2170 results
It is estimated that 7 percent of patients who develop cancer as a child have a tumor predisposition syndrome (TPS)(Merks et al, Am J Med Genet A, 2005). It is of significant clinical relevance to recognize a TPS as it may lead to recognition of…
Patients suffering from high risk or relapsed leukaemia or high risk MDS can only occasionally be cured with conventional chemotherapy. Allogeneic stem cell transplantation (allo-SCT) has substantially improved the outcome of such patients due to a…
With implementation of the APWR we expect a reduction in the total amount of radiographs requested, without missing any clinical relevant fractures. We also expect a reduction in overall waiting times at the ED and a total amount of cost savings…
Primary: There is no difference in satisfaction between patients who filled out their PROMs and received feedback compared to patients who did not. Secondary: There is no difference in illness behavior (empowerment), patient-physician relationship…
A more rapid rise of the levodopa plasma level after inhalation compared to oral administration of levodopa.
We expect that, compared to a standard text-only, a leaflet with pictograms leads to better perceived comprehensibility, utility and design quality of the leaflet by consumers. This could lead to better recall and understanding of the drug…
Dupuytren's disease is a progressive disease and often recurs. We will measure increase in degrees of extension deficit 3 and 6 years after treatment with CCH.
Based on 1) the improvement in survival of both younger and elderly pPCL patients by incorporation of novel agents (especially proteasome inhibitors and lenalidomide) and 2) improvement in survival for younger patients by using auto-SCT in treatment…
To assess the safety and efficacy of endovascular renal nerve ablation in patients with systolic heart failure.
In the process of developing a serious game for testing patients’ level of myocontrol a part of the test needs to be validated. In a previous trial we found differences between several tests that need further inspection. The current study focusses…
The central hypothesis of our study is that routine postsurgical anesthesia visits reduces postoperative 30-day mortality by 30%.
Hypothesis 1: We expect to find an approach bias in forensic sexual offenders and in sexual addicts. Hypothesis 2: The proposed intervention will cause a decline in approach bias in forenisc sexual offenders and sexual addicts, compared to the…
Does intensive multifactorial coaching of patients with chronic renal insufficiency by nurse practitioners result in a reduction in cardiovascular events, cardiovascular mortality, all cause mortality and change in decline of renal function.
The objective of this prospective randomised, double-blind, controlled trial is to evaluate the effect of OPEP use on respiratory symptoms in patients with COPD or chronic bronchitis with excessive mucus in daily clinical practice.
Inhalation of once daily double dose of inhaled tobramycin targeted to the small airways by the Akita (1x 300 mg instead of 2x 150 mg) is more effective in reducing small airways obstruction compared with standard of treatment: twice daily…
the active treatment group has an improvement of at least 10 points of DASH functional outcome more than the placebo group.
We hypothesize that: (1) GPs who receive the ASBI implementation program will increase screening and brief intervention delivery rates relative to GPs in the control condition; (2) GPs involved in the ASBI implementation program will have a…
Protein feeding prior to surgery enhances muscle and bone protein synthesis rates in the post-prandial period when compared to the non-feeding condition in older patients undergoing total hip arthroplasty.