2174 results
The purpose of this project is to investigate the presence and course of neo-antigen specific immunity in patients with polymerase epsilon (POLE) mutated endometrial cancer, with the intent to exploit the obtained knowledge of neo-antigen specific…
To compare accumulation of liver fat (as measured using CAP) and liver fibrosis (as measured using fibroscan) between patients with quiescent and active inflammatory bowel disease
With this research project we will investigate the relationship between SSRI concentration in the (pre)term neonate and clinical short and long term effects on the neonate after exposure to SSRI*s during pregnancy and lactation. Furthermore, the…
Determining the role of duplex ultrasound in patients with a clinical suspicion for temporal arteritis.Determing the sensitivity, specificity, negative predictive value and positive predictive value of duplex ultrasound in patients with a clinical…
The primary objective of the study is to assess the feasibility to treat type II endoleaks with Aneufix ACP-T5 successfully.The secondary objectives of the study are to assess the:- Clinical success rate defined as Occurrence of adverse events and…
The main purpose of this pilot study is to assess the feasibility and potential efficacy of implant retained mandibular advancement device (MAD) therapy on a small scale in edentulous patients with mild to moderate OSA in comparison to CPAP therapy…
Primary Objective: To further optimize the IPMDSSecondary Objective(s): To determine in which age-groups the items within the IPMDS are appropriate To determine whether the IPMDS can assessed reliably by research nurses, students and physician…
To evaluate the additional effect of coal tar treatment to a corticosteroid regimen in adults (aged >16 years of age) with moderate to severe atopic dermatitis, based on the percentage change in Eczema Area and Severity Index (EASI) at week 2…
Primary objectivesTo study if LcS can colonize the esophagus of BE patients.To study the effect of LcS colonization on the Gr+ (except for LcS)/ Gr- bacterial ratio of the esophagus.Secondary objectivesTo quantify the number of specific pathogenic…
To analyse serum sodium concentration, serum osmolarity and arterial bloodgas at different times before and after administration of HTK solution, to get more insight of the impact of this solution on these biochemical parameters and to improve our…
Primary Objective: to determine if lactate can be continuously and reliably measured by microdialysis in subcutaneous tissue in healthy volunteers
The primary objective of this study is to determine the efficacy of vitamin D supplementation on the severity of PN in patients with multiple myeloma.
The objectives of the study are twofold:1) Determination of the absolute values and variability of PSMA uptake in tumour tissue and in normal tissues, including muscles, liver, spleen, bone marrow2) Determination of the absolute values and…
To identify novel childhood osteosarcoma predisposing genes.
To assess and compare the gastric emptying rate and gut hormone levels between patients one year after standard RYGB (S-RYGB), B-RYGB and EP-RYGB.
The overall objective of this study is to understand how consumers adapt their oral processing behaviours in response to small texture variations of yogurts and how changes in oral processing behaviour of yogurts impact the amount of food eaten and…
To investigate whether enhanced expression of growth factor receptors (FGF-R, PDGF-R and VEGF-R) and increasedvascular cell proliferation in the lung of IPF or PAH patients can be assessed using [11C]-Nintedanib or [18F]-FLTPET/CT imaging.
The purpose of this research project is to improve the overall quality and resolution of the MRI images, to correct for movement effects during the procedure and to speed up the investigation. The goal is to enhance and standardize a technique…
Primary objective: To prospectively evaluate the lesion (AN-)count, i.e. abscesses, inflammatory nodules, and draining sinuses, in the axilla treated with MWA compared to the untreated contralateral axilla after six months.Secondary objectives: - To…
Primary Objective* To assess the association between changes in the number of nocturnal voids and change in Nocturia Sleep Quality Scale (NSQS) total score in adult subjects with nocturia due to Nocturnal Polyuria (NP)Secondary Objectives* To assess…