85 results
Determine speech understanding in noise with the AB*s bimodal BF directional hearing technology.
Confirm the technical performance of the new IMPERIA Delivery System and evaluate the safety and efficacy of the entire ALLEGRA THV System.
To assess the feasibility of participants positioned in an MRI scanner to regulate their breathing based on biofeedback
Primary Objective: To investigate if treatment according to the EMDR protocol for urge reduce daily scratching behaviour in PN patientsHypothesis: Treatment according to the EMDR protocol for urge leads to a statistically significant reduction of…
The primary objective is to determine whether there is a difference in the capability of the patients to successfully follow the instructions of both the Levodopa Cyclops* and the INBRIJA® inhaler during an off episode, based on the instruction…
To evaluate how the 3D knee joint space distribution in knee OA patients changes under the influence of weight-bearing (upright) and flexion MRI scanning.
Certain drugs are administered by using an inhaler (puffs). An inhaler may contain propellant to get the right amount of the medicine into the lungs in the right way. Some of the propellants used in inhalers are greenhouse gasses and are therefore…
To study the possible epigenetic modifications in sperm cells after BCG vaccination
Primary Objective:The primary objective is to investigate whether the retinal SpO2 - measured with invisible, NIR light - changes as a function of simulated height in the same way as the SpO2 measured with the standard finger clip.Secondary…
The main objective of the proposed study is to investigate the effect of PNS as a means to support the learning process in order to accelerate learning and improve knowledge and competence retention. This will be tested by applying PNS stimulation…
To assess the feasibility of using a subtherapeutic dose of piracetam as a marker of adherence to therapy by determining whether this subtherapeutic dose produces a detectable concentration in the urine
Objective: The aim of the present study is to study the effect of increased adrenaline levels on the inflammatory response (e.g. leukocyte phenotype, cytokines, inflammatory proteins) by administering exogenous adrenaline. Secondary aims consist of…
The main objective of the proposed study is to investigate the effect of ctVNS as a means to counteract the effects of SD on cognitive performance during and after SD. This will be tested using both well-controlled, established cognitive desktop…
Primary objectiveThe primary objective is to determine whether 3-MMC can be safely administered in healthy volunteers in doses up to 100 mg. Participants will be monitored by a medical doctor and vital signs, laboratory safety and side effects will…
The study will consist of 3 parts. First we want to perform a reference study with healthy volunteers to investigate the viability of 4DCT scanning of the wrist for evaluating wrist bones configurations and movements (translations and rotations)…
The objective of this study is to evaluate the gastro-intestinal tolerance, nutritional intake, and acceptability of an adjusted composition of an enteral tube feed for adults in need of long term nutritional support.
The objective of the study is to investigate the feasibilty, acceptabilty, implementation and preliminary (cost-)effectiveness of the intervention on recovery, health and lifestyle variables.
Primary:• To evaluate the clinical benefit rate (CBR) of ixabepilone Secondary:• To evaluated progression free survival (PFS)• To evaluate overall survival (OS)• To evaluate objective response rate (ORR) defined as Complete Response (CR) and Partial…
Primary objectiveThe primary objectives of this feasibility clinical investigation are to assess the overall usability of the Philips AirWaze investigational device as measured by the System Usability Score (SUS), and the accuracy of the tool-in-…
In this study we will investigate how safe the new compound ARGX-119 is and how well it is tolerated when it is used by healthy subjects.We also investigate how quickly and to what extent ARGX-119 is distributed and eliminated from the body. In…