140 results
A post marketing surveillance study to assess safety, clinical performance and survival of the uncemented Glenoid Affinis vitamys Uncemented Glenoid Affinis Vitamys total prosthetic shoulder replacement. All implants already bear the CE-marking.
Primary Objective: To study the effect of different treatment approaches - existing of conservative management, pharmacological treatment and surgical treatment - on sexual function in patients diagnosed with endometriosis. Secondary Objective(s):…
The objective of this pilot study is to assess whether transportation of the sample via a pneumatic tube system (PTS) has any detrimental effects on the recovery of presepsin levels, when compared to traditional hand-delivery. This research will be…
Primary Objective:The study aims to assess freedom from AF ten years after the procedure without the use of antiarrhythmic drugs in patients who underwent thoracoscopic ablation in advanced AF with or without GP ablation. Secondary Objectives:1. To…
To assess the post-operative quality of recovery after robot-assisted as compared to open extended lateral pancreaticojejunostomy.
The primary objective is to perform a clinical validation of the analytical method for dried blood spot microsampling of cabozantinib, pazopanib, sunitinib, Lenvatinib, nivolumab, ipilimumab, pembrolizumab, atezolizumab or bevacizumab. The secondary…
The objective of this study is to accumulate clinical data on the safety and performance of NBGM200 embolization in patients with degenerative OA of the knee refractory to conservative treatment so as to provide evidence of conformity with…
The main objective is to replicate the results of the recent successful efficacy study on precuneus rTMS in AD by Koch et al. (2022). Secondary objectives include investigating what functional brain activity/network changes underlie the effects of…
The objective of this project is to test the clinical and cost effectiveness of utilizing the assessment of transdiagnostic dynamics of symptoms to provide a personalized e-health treatment intervention as an automated tool during the waiting list…
The primary objective of the study is to determine whether AVIM therapy in combination with medical therapy is more effective at reducing ambulatory systolic blood pressure (aSBP) and to determine whether AVIM therapy is safe.
The objective of this study is to demonstrate the clinical performance of VENTANA PD-L1 (SP263) CDx Assay in terms of its ability to identify patients with metastatic NSCLC who may benefit from treatment with acasunlimab (GEN1046) in combination…
Primary objectives1. To determine the effect of a tailored exercise program by using the widely implemented exercise app *Physitrack* on experienced pain and fatigue in patients with FSHD.2. To investigate the relationship between perceived pain and…
The main objective of this study is to determine the maximum tolerated dose (MTD) of 5 fractions MRgRT for patients with AC following FLOT therapy. The secondary objectives are feasibility, non-dose limiting toxicity, oncological outcomes and to…
The purpose of this study is to determine the feasibility of sports-specific CTR in athletes.
Primary Objectives are to• identify novel (likely) pathogenic genetic variants in familial or young AF patients.• investigate the relation between genetic profiles and electrical (AF) phenotypes.• develop a specific gene panel for AF• construct a…
This study has been transitioned to CTIS with ID 2024-520305-39-00 check the CTIS register for the current data. Primary objective: to evaluate the efficacy of LSD 25µg every 3 days for 3 weeks in cCH. Additional objectives:- To evaluate the safety…
The aim of this clinical study-part in the Netherlands is to identify demographic and clinical predictors of risk, diagnosis, and progression of heart failure. In the European study component, the objective is to eventually compute with this…
Investigate the effect of FMT from healthy obese donors on objective response rate (ORR according to RECIST criteria) in patients with metastasized or locally advanced NSCLC receiving standard of care first-line immunotherapy with or without…
To investigate the influence of body posture on the measurement cervical sagittal balance parameters.
The primary objective of this study is to compare the mean binocular DCIVA at 66 cm under photopic conditions 3 months after cataract surgery, in a series of patients, who previously underwent myopic laser surgery, bilaterally implanted with the non…