4653 results
The purpose of this prospective study is to evaluate the value of 18F-FDG PET/CT and CT for preoperative regional N staging of bladder cancer and to verify the results by comparison with histopathological analysis, the gold standard.
The aim of this present diagnostic study is to determine the accuracy by which we can detect residual disease after neoadjuvant chemoradiotherapy.
Specific AimsAs reviewed above, childhood anxiety disorders are highly prevalent and debilitating, and there is an urgent need for improvement of current treatment strategies. An innovative, but scarcely examined, treatment option for childhood…
Objectives: 1. To assess the prevalence of pain in elderly with dementia and to study the relationship between the various subtypes of dementia and the presence of specific types of pain(e.g. nociceptive pain, neuropathic pain, and orofacial pain).…
The primary objective of the study is to assess the safety and tolerability of long-term open-label CP-690,550 therapy in subjects with CD.Secondary objectives are to evaluate the effect of CP-690,550 maintenance therapy on clinical remission and on…
The primary objective of this study is to demonstrate the clinical performance of PRO-Kinetic Energy stent in subjects with atherosclerotic disease of native coronary arteries.
The aim of this project is to investigate the association between clinical and genetic factors and DDAVP response in MHA patients and to determine their relative contributions to the DDAVP response.
To assess the correlation between the presence of GIP in urine/ faeces and symptoms after a single dose gluten provocation (mimicking the daily risk of gluten ingestion) in patients with coeliac disease adhering to a strict gluten-free diet.
The primary objectives for Part 1:-To determine the recommended Phase II dose of RO5424802 to be used in Part 2 of the study-To evaluate the safety and tolerability of 600mg and 900mg doses of RO5424802 administered twice daily to subjects with…
This study investigates the optimal intraoperative treatment algorithm to lower glucose in patients with diabetes mellitus type 2 undergoing non-cardiac surgery, comparing intraoperative glucose-insulin-potassium infusion, insulin bolus regimen and…
In this prospective study we aim to find out whether an early refeeding strategy in addition to standard care can improve maternal and neonatal outcome and reduce hospital stay.
In the current study, we want to demonstrate Rienso uptake in the vessel wall in patients with cardiovascular disease and relate the uptake of Rienso to endothelial permeability.
The primairy objective of this fase II study, is to compare two treatment regimens of vismodegib in two populations of patients with multiple BCC's (patients with Gorlin syndrome and patients who do not have Gorlin syndrome). Primary to assess…
The project has three main scientific objectives: (1) To investigate how speech processing with CIs affects listeners* mental representations at lexical and sub-lexical levels, as well as the flow of information between these levels; (2) To study…
To map phenomenolocal characteristics of hallucinations and delusions in psychiatric and neurologic patient populations as well as in the general population. By comparing this between all groups, different subtypes of hallucinations and delusions…
Currently, only few publications exist which describe MRI for esophageal cancer. Therefore, the objective of the study is to develop a MRI protocol for imaging of this organ. The research will particularly be focussed on functional MRI. Those scans…
The primary objective of the proposed study is to examine the neural substrate of cognitive and social-emotional apathy in patients with schizophrenia. Secondary, we intend to explore the concentration of brain metabolites and structural differences…
1) Main Objective: To investigate the validity, reliability and feasibility of the Clinician*s Rating Scale for evaluating impaired self-awareness and denial of disability after brain injury (CRS-ISA-DD) for use in the Dutch clinical practice.2)…
To validate spectral analysis of the fHRV as a new method for fetal monitoring. To determine the exact influence on fHRV of several commonly used medicines in obstetric care; namely tocolytic drugs, corticosteroids, antihypertensive agents,…
Primary Objective(s): 1. To obtain preliminary data on whether (and to which extend) adjuvant chemotherapy for colon cancer results in (a) deterioration of contractile muscle properties and increased muscle fatigability, (b) increased inflammation…