3040 results
In the present study we are interested in the interaction between these two deficits in patients with schizophrenia using faces as visual objects. One of the important issues that will be addressed is that if the emotional content represented by the…
To evaluate detection thresholds, functioning of the HPA-axis and risk of chronic pain in children of 5-years of age who experienced pain and received morphine in neonatal period in compare with children of 5-years of age who experienced pain…
1. This study aims to compare the accuracy of EUS/EBUS and PET-CT as restaging tools in patients treated with induction therapy for stage IIIA or IIIB NSCLC.2. To study the additive value of immune histochemical staining of adequate biopsies…
Objectives* The primary aim is to study the kinetics of QFT-G in military personnel with a positive TST result. * Secondary aims are to study the practical feasibility of using QFT-G in the setting of a military hospital.Next to this we wish to…
To determine the objective response rate (ORR) (complete response and partialresponse) of RAD001 10 mg po qd monotherapy in patients with advanced(unresectable or metastatic) pancreatic NET after the failure of cytotoxicchemotherapy.
Main goal is to gain more insight in the role of dopaminergic neurotransmission in rewards, motivation and the attribution of salience in the etiology of psychosis. Primary question is whether a change in blood oxygation level dependent (BOLD) fMRI…
We found a prevalence of 6% sensitization in patients with a possible food allergy. The aim of this study is to investigate if sensitization to lupine flour in atopic patients has clinical relevance. Additionally, we want to investigate if cross-…
Aim of the present study is to determine · whether and to what extent nadroparin is excreted by CVVH · whether the drug accumulates during CVVH as measured by anti-Xa activity and endogenous thrombine potential (ETP)· whether clearance of nadroparin…
The primary objectives are:* to determine the effect of steady-state concentrations of TMC114 coadministered with a lowdose of ritonavir on the steady-state pharmacokinetics of ddI,* to determine the effect of steady-state concentrations of ddI on…
To compare colonic stenting followed by elective surgery with emergency surgery for the management of acute left-sided malignant colonic obstruction in terms of health-related quality of life, morbidity and mortality.
The aim of the study is to improve the diagnostic tools of spontaneous bacterial peritonitis.The primary aim is to evaluate the use of dipsticks as bedside diagnostics compared to the current standard polymorphonuclear leukocyte count in identifying…
The objective of this study is to determine the influence of ambient noises upon the characteristics of fMRI signals that are of relevance in connectivity measurements.The study will focus on the influence on the statistical properties of measurable…
To determine the efficacy of two dose regimens of HuMax-CD20 in patients with Follicular Lymphoma who are refractory to rituximab in combination with chemotherapy or to rituximab given as maintenance treatment.
Primary objective* To evaluate the efficacy of IAT in addition to BMM compaed to BMM alone in terms of favourable outcome at 90 days, defined as a modified Rankin score of 0-3, in patients with an acute ischemic stroke caused by basilar artery…
Primary: To evaluate the long-term safety profile of BG00012.Additional: To evaluate the long-term efficacy of BG00012 using clinical endpoints (including relapse and annualized relapse rate [ARR]) and disability progression (Expanded Disability…
Primary objective:The main purpose of the study is to develop a new concept of micro-based flow devices to detect (i) a prethrombotic state, (ii) the efficacy of established and novel antithrombotic medication, (iii) insufficient hemostasis and…
Primary; • To study the mitochondrial respiration in human BATSecondary;• Apply histological protein stainings and mitochondrial content analysis of human brown adipose tissue • Relate mitochondrial activity and content to the amount of UCP1, body…
Primary:The primary objective of this study is to demonstrate that the overall progression-free survival (PFS) of 8 cycles of intermittent (2 times 4 cycles) chemotherapy (paclitaxel) is not inferior in efficacy, compared to 8 continuous cycles of…
The primary objective for this study is as follows:* To evaluate clinical benefit in terms of PFS, as assessed by an IRF, for GA101 when used incombination with bendamustine compared with bendamustine alone in patients with indolentNHL refractory to…
The aim of the trial is to individualize treatment for each patient by adapting it to early response and to treat only those patients with addiotional radiotherapy who show an inadequate treatment response. The degree of treatment response is…