187 results
To establish normal ranges for the lateral ventricles in neonates with a gestational age ranging from 25 to 42 weeks.
We intend to study the role of fronto-striatal circuitry and cognitive control in the inflexible behaviour that is a defining feature of autism.
To obtain insight in the role of the innate immune response, especially Type 1 interferons, in the pathogenesis of RSV LRTI. New techniques are used to unravel the local (nasopharyngeal) immunological milieu during viral LRTI. The hypothesis is that…
To evaluate the efficacy of TESE and to describe the risks of the TESE procedure for the men with a four year follow-up of their offspring.
zie bovenstaand
Registry is the core study of the European Huntington*s disease Network (EHDN). The aim of the Registry study is to collect prospective data on the phenotypical characteristics of Huntington's disease (HD) mutation carriers regardless of…
The current project aims first to examine whether IPT produces outcomes that are superior to the comprehensive treatments already available ('care as usual'). Primary outcomes include parenting behavior and the quality of the parent-child…
Primary Objective: To investigate the effect of treatment with nebulized rhDNase on pulmonary function in children with asthma and persistent obstructive pulmonary function.Secondary Objectives: To investigate the effect of treatment with nebulized…
Impact of introduction of real-time viral PCR on clinical decision making and costs in children with a respiratory tract infection.
The purpose of this study is to show that participation in an exercise programme will increase the exercise tolerance, musle power and health-related quality of life and will diminish the degree of fatigue in children on dialysis.
To examine the effect of surgical trauma on mucosal perfusion, intestinal epithelial damage, the inflammatory response and potentially sepsis, following surgery remote to the abdomen in adults, children and neonates,
Determine whether temozolomide given during radiation therapy followed by the combination of temozolomide and CCNU as adjuvant therapy results in an improvement in event-free survival compared to historical control cohorts.To further assess the…
To investigate the correlation between androstenedion in saliva and serum in all patients that have a request for androstenedion in serum.To collect age related reference ranges for healthy children on three different time points.
To establish: 1) the effectiveness of adenoidectomy compared to a non-surgical strategy in children in terms of reduction of upper respiratory tract infections (with or without fever) and improvement in quality of life 2) the costs-effectiveness of…
The objective is to investigate wether a brief CBT with parental involvement among children and adolescents with ASD reduces the risk of PTSD compared to a waitlist control group.
1. Development of a prevention strategy for CD in children from high risk families for the disease by induction of oral tolerance to gluten;2. Identification of the immunological mechanisms involved in initiating the aberrant response to gluten…
The Municipal Health Service The Hague and the LUMC are planning to conduct a study similar to the one in Pune in The Hague. In the start-up phase of this study we are preparing a pilot study in which we will study anthropometry and insulin…
Objectives. The goals of the current protocol is therefore the natural follow-up of the objectives achieved with the previous grants and, in particular, of projects designed to discern new models for the successful conduct of clinical trials in…
The purpose of this study is to determine if the development of idiopathic scoliosis is related to neuropathic detrusor/sphincter dyssynergia. When bladder and sphincter function are disturbed, adequate therapy can be started in an early phase to…
Primary objectives1. What is the pulmonary function and exercise tolerance in children born with esophageal atresia at the age of 8-18 years (group I), determined by spirometry, measurement of lung volumes and a maximal exercise test. 2. What is the…