72 results
We intend to study the role of fronto-striatal circuitry and cognitive control in the inflexible behaviour that is a defining feature of autism.
To evaluate the efficacy of TESE and to describe the risks of the TESE procedure for the men with a four year follow-up of their offspring.
zie bovenstaand
Registry is the core study of the European Huntington*s disease Network (EHDN). The aim of the Registry study is to collect prospective data on the phenotypical characteristics of Huntington's disease (HD) mutation carriers regardless of…
Primary Objective: To investigate the effect of treatment with nebulized rhDNase on pulmonary function in children with asthma and persistent obstructive pulmonary function.Secondary Objectives: To investigate the effect of treatment with nebulized…
The purpose of this study is to show that participation in an exercise programme will increase the exercise tolerance, musle power and health-related quality of life and will diminish the degree of fatigue in children on dialysis.
To examine the effect of surgical trauma on mucosal perfusion, intestinal epithelial damage, the inflammatory response and potentially sepsis, following surgery remote to the abdomen in adults, children and neonates,
Determine whether temozolomide given during radiation therapy followed by the combination of temozolomide and CCNU as adjuvant therapy results in an improvement in event-free survival compared to historical control cohorts.To further assess the…
To show that treatment with SUBLIVAC® Grasses is clinically effective by means of reduction in allergic symptoms and/or use of allergic symptomatic medication in subjects suffering from IgE mediated allergic complaints triggered by grass pollen.
The objective is to investigate wether a brief CBT with parental involvement among children and adolescents with ASD reduces the risk of PTSD compared to a waitlist control group.
The main objective of this research proposal is to 1). develop an on-line monitor for young athletes to prevent them from a systematic overload and to avoid overtraining 2) develop clinical tools to improve diagnostics of overtraining.
Objectives. The goals of the current protocol is therefore the natural follow-up of the objectives achieved with the previous grants and, in particular, of projects designed to discern new models for the successful conduct of clinical trials in…
The purpose of this study is to determine if the development of idiopathic scoliosis is related to neuropathic detrusor/sphincter dyssynergia. When bladder and sphincter function are disturbed, adequate therapy can be started in an early phase to…
Primary objectives1. What is the pulmonary function and exercise tolerance in children born with esophageal atresia at the age of 8-18 years (group I), determined by spirometry, measurement of lung volumes and a maximal exercise test. 2. What is the…
1. To improve patient's quality of life in a cost-effective way by a self-management programme guided by doctors and a specialist asthma nurse through information and communication technology. 2. To investigate whether a simple index of asthma…
Determine feasibility and reliability of CDFM in relation to the current strategy of intermittent Doppler US examinations for detection of hepatic artery thrombosis.
Revision of the reference values for aerobic capacity in healthy Dutch boys and girls aged 4-13 years using the Bruce treadmill protocol.
Both in emergency departments and in prehospital services (ambulances and MMTs) effort is being done to find a fast alternative for the screw-tipped bone needle that has the least amount of risk and complications.The aim of this study is to analyse…
To determine the feasibility and applicability of the intervention 'Traject' to improve the participation in work of young adults (16-25 years) with a chronic disorder.
To evaluate the efficacy of inhaled rhDNase in addition to conventional treatment in children with an atelectasis during mechanical ventilation.