172 results
To establish biomarkers in nipple aspirate fluid, follow them in time and link them to breast cancer development at its earliest stage in women at high risk for breast cancer. Threshold values of biomarkers will be determined that point to a…
Are changes in cognitive functioning related to structural changes in the brain in patients with type 1 diabetes mellitus. How are these changes related to diabetic complications like duration of chronic hypoglycaemia, disease duration and presence…
The primary objective is acquiring insights in the development of BOS in patients after human lung transplantation in an early phase of the disease which can be used to improve immunotherapeutic handling in order to prevent or delay the onset of BOS…
In this study the prevalence and kind of sexual and psychosexual problems will be assessed. Psychological well being is studied as well
To evaluate the efficacy of TESE and to describe the risks of the TESE procedure for the men with a four year follow-up of their offspring.
To examine cellular damage, intestinal barrier function loss, activation of the Complement system and inflammatory alterations induced by ischemia and reperfusion of the human small and large intestine.Second, we aim to study the consequences of…
Registry is the core study of the European Huntington*s disease Network (EHDN). The aim of the Registry study is to collect prospective data on the phenotypical characteristics of Huntington's disease (HD) mutation carriers regardless of…
To examine the effect of surgical trauma on mucosal perfusion, intestinal epithelial damage, the inflammatory response and potentially sepsis, following surgery remote to the abdomen in adults, children and neonates,
the investigation and evaluation of certain serummarkers for inflammation and tumoractivity during the followup of colorectal neoplasms, and the applicability of these markers during the followup of these patients or the evaluation of the effect of…
Objective of this study is to provide evidence for the induction of AGEs in blood and tissue in patients with septic shock.
In previous studies we have identified specific receptor and surface protein expression profiles on neutrophils. Some of these profiles point at partially refractory neutrophils. In the current NERTHUS study we have seen that circulating neutrophils…
In this study we will study the incidence of QTc-interval prolongation when combinations of 2 or more QTc-prolonging drugs are prescribed. Also we will investigate if QTc-prolongation is more frequent in patients with higher drug plasma…
The primary hypothesis of our study is that volumetric monitoring will allow for more effective and targeted fluid administration compared to pressure (PAC) monitoring, thereby allowing the attending physician to better optimize fluid infusion…
Exploring the incidence of fatigue after sarcoidosis, its severity and nature. Next we will try to associate fatigue with capacity to produce pro- and anti-inflammatory cytokines.Our secondary objective is testing the activity of the HPA-axis, the…
The main aim of this study is to assess the prevalence of allergic and non-allergic health problems in veterinary students in different phases of the veterinary education. On later stage, genetic predisposition for allergies will be studied. In the…
The purpose of this study is to determine whether optical mammography performed on the PMS DOT has a potential in breast cancer diagnosis in patients with suspicious breast lesions.
The expectation is that FDG-PET demonstrates or excludes infectious complications earlier than current practice, resulting in more efficient use of other diagnostic methods and therapy. Besides early detection and treatment of invasive fungal…
The general objective of this study is to elucidate the cellular components for HIV-1 infection in children.
The primary objective is identification of a set of genes as candidate monocyte markers for acute coronary complications and subsequent identification of a prognosis classifier to discriminate vulnerable, stable, and control subjects, based on the…
To determine the mean systemic filling pressure, the arm-occlusion pressure, the cerebral zero flow pressure and their response to changes in volume status and vasoactive medication. To evaluate and confirm the value of mean systemic filling…