3999 results
The aim of this proposal is threefold: (i) test a neuroscientific model of prosocial development by relating neuroscience discoveries to changes in several dimensions of prosocial development in a comprehensive study including children, adolescents…
In this study, the aim is to perform a clinical evaluation of the NovioMini in children during behavioural bladder training to examine the performance of the NovioMini as a full-bladder-based notification system during natural bladder filling.
(1) To compare adenoma miss rates (AMR) between Endocuff Vision-assisted colonoscopy (EAC) and conventionalcolonoscopy (CC)(2) To compare adenoma detection rates (ADR) between EAC and CC(3) To assess whether a proposed increased ADR and reduced AMR…
1) To evaluate changes in microvascular resistance of the infarcted area in the first hours after ST-elevation myocardial infarction and during the recovery period (<5 days)2) To classify patients according to recovery of microvascular…
Concordance between MET diagnosis with and without the use of ultrasound with the chart review definitive diagnosis will be studied. Also other secondary endpoints will be evaluated.
Objective: The primary objective of this study is to investigate whether pain experience decreases or increases when cognitive functions decline in patients with Parkinson's disease. Furthermore will be investigated whether this is influenced…
We hypothesize that verapamil reduces progression from paroxysmal to persistent AF, improves rate control, exercise tolerance and quality of life and reduces costs compared to metoprolol.
Measuring cardiac output using TTE with and without the use of ProbeFix in adult Intensive Care patients in which a PLR test is used as a fluid challenge. The possible changes in cardiac output measured with TTE are compared with the measurements…
The primary objective for this trial is to assess the local cancer control achieved with FLA in patients with localized low to intermediate risk prostate cancer (Gleason 3+3, 3+4 or Gleason 4+3).Secondary objectives are to determine effectiveness of…
A. To gain more knowledge about the prevalence of TBI in male prisoners in the PPC and the relationship of TBI with violent crime and aggression. We expect that TBI is more common in violent offenders than in non-violent offenders. More specific, we…
Aim of this pilot study is to determine which intervention groups are feasible in a larger trial which aims to a compare postoperative pain and complication rates in moderate versus deep neuromuscular blockade, and normal versus low intra-abdominal…
[1] To develop robust assays for quantification of novel CSF/blood biomarkers of CAA.[2] To determine the contribution of CAA to cognitive decline in dementia and ICH patients, using CAA-specific biomarkers
The aim of this study is to investigate the effects of DMF (Tecfidera) on the association between fatigue and fatigability measures in pwRRMS starting with DMF medication.
The aim of this pilot study is to assess the effect of low intensity mastication training in patients with a mitochondrial disease on masticatory performance, efficacy, endurance, bite force and the feasibility of this training .
To investigate associations between IBD severity, ASCA titer, microbiota composition and C. albicans strains present in feces.
The randomized controlled trial (RCT) will be performed at Karakter Child and Adolescent*s Psychiatric Hospital and will be implemented at all locations, spread out over three provinces in The Netherlands. The project aims:1. To explore the…
Primary Objective: To determine the safety and tolerability of NF135.C10 sporozoite immunization under chemoprophylaxisSecondary Objectives:• To determine the dose-dependent protective efficacy of NF135.C10 CPS-immunization against homologous…
To assess the provoking effect of partial sleep deprivation on paroxysmal neurological events in a EMU setting, in people with possible epileptic seizures.
Primary Objectives: * To determine if NA patients have altered cerebral activity related to motor planning of their affected arm compared to healthy controls and compared to their non-affected arm.* To determine if specific rehabilitation focused on…
The primary objective of this study is to analyse the microenvironment of the primary tumour and sentinel and non-sentinel lymph node(s) (i.e. various T-cell populations, antigen presenting cells and myeloid-derived suppressor cells) in patients…