21 results
Primary research questions:1. Does tinnitusspecific- behavioural exposure-treatment (T-BET) decrease tinnitus-related fear, tinnitus-severity and enhance recovery, when compared to a masking-therapy with use of personalised on-ear masking-devices,…
The aim of the study is to examine the effectiveness of Rock and Water (R&W) and possible moderators and mediators. Effectiveness: - The R&W program will increase students’ socio-emotional adjustment (i.e., psychosocial wellbeing,…
A disease control of 60% is expected and will be clinically relevant with a lower reference bound of 45%.
The majority of adolescents in the Netherlands has an inadequate consumption of fruit, vegetables, fibers and an excessive consumption of energy-dense, nutrition-poor foods. Unhealthy diets result in an increased risk of overweight, obesity and…
Nebulizing amoxicillin clavulanic acid is more effective for reaching amoxicillin levels in sputum > MIC90 than amoxicillin clavulanic acid given by oral or intravenous administration.
Time to recurrence of sustained VT (longer that 30 seconds or with hemodynamic instability) or VF with or without documented ICD therapy (shock or ATP) for VT of VF will be longer in patients randomized to substrate based ablation than in patients…
The investigational formula will be equivalent to the control formula with regard to the postprandial blood lipid parameters.
Does the use of two different balanced hydroxyethyl starch solutions, influence the coagulation profile, acid-base status, ionogram, colloid oncotic pressure and organ function in patients undergoing cardiopulmonary bypass.
To develop a dosing nomogram of irinotecan in patients homozygous polymorphic for UGT1A1*28 and/or UGT1A1*93 in order to reduce the incidence of severe irinotecan-associated toxicity, defined as febrile neutropenia in the first 2 cycles (amendment…
Acutely hospitalized older patients frequently suffer from inadequate sleep. Insufficient sleep can lead to patient distress and delayed recovery from acute illness or a surgical procedure. Currently, no evidence-based treatments exist for sleeping…
1. A decrease in cocaine use over a three month period in participants who receive AAT training as opposed to VPT training. 2. A change in symptoms involving craving, the urge to use, withdrawals well as stated readiness to change in participants…
Treating a symptomatic urinary tract infection in patients with a long-term indwelling catheter for 5 days is non-inferior compared to the standard duration of 10 days of antibiotic therapy with regard to clinical cure rate.
Preventive group support for 6 to 8 years old children after parental divorce or separation, leads to: - more positive child functioning; - decreased emotional and behavioral problems of participating children; and - increased child wellbeing;
The disease free survival will be prolonged in MAGE-A3 positive patients treated with recMAGE-A3.
The goal of this study is to identify and validate recently discovered and novel biomarkers of pathophysiology, diagnosis, classification, disease activity, prognosis, treatment susceptibility, and treatment efficacy in chronic inflammatory…
We hypothesize that catheter based selective renal denervation of the native kidneys in renal transplant recipients will improve blood pressure control and diminish the number of antihypertensive drugs.
1) Surveillance of patients with a urine test, followed by cystoscopy only when the urine test is positive, results in detection of a the same or a higher number of recurrences and is cost-effective and 2) urine diagnostics contribute to earlier…
The objective of this proof-of-concept study is to test in no-option CLI patients whether ARA 290 (a) reduces limb pain, (b) reduces signs of local and systemic inflammation, and (c) promotes wound healing.
The aim of the study is to show non-inferiority of a short, flare-up GnRH-agonist protocol to the GnRH-antagonist protocol, both with OC pill pre-treatment, in women undergoing in vitro fertilisation (IVF) or intracellular sperm injection (ICSI)…
The use of SBAR by Community Nurses will improve their selfefficacy and empowerment.