2320 results
The primary objective is to evaluate the feasibility of ICG-enhanced near-infrared qFME to determine tumour demarcation and tumour depth in upper GI tumours (e.g. HGD or superficial oesophageal and/or gastric adenocarcinoma (T1)) during ESD.
The REPLACE study aims to determine whether not changing the catheter (catheter retained) for catheter-associated urinary tract infections (CAUTI)affects the recurrence-risk of CAUTI.
To explore whether vigorous endurance exercise (i.e., running a marathon) alters the magnitude of cardiac damage following myocardial ischemia-reperfusion injury in amateur athletes through using an ex vivo rat heart model of myocardial infarction.
Primary objective: - To study the diagnostic accuracy of PCCT (± CT-derived fractional flow reserve [FFRct]) as compared to the reference standard ICA (± FFRinv) in the NSTE-ACS population referred to the UMCG. Secondary objectives: - To study the…
This is a pilot study for investigating the cause of recurring cerebral thrombo-embolic events in a patient after (branched) TEVAR surgery. The main aim of this logistical pilot is to develop a workflow for investigating blood flow patterns in such…
The aim of this study is to better understand the relation between cognition, sensory functions and motor control for speech in older age. Thereby, we strive for improved speech-based discrimination of typical aging from neurodegenerative declines.
Our overall aim is to develop mid-field MRI systems for low-threshold, extramural service to GP practices that can contribute to making healthcare more sustainable. In this study we want to perform the first steps towards this general aim. On one…
In this pilot study, we aim to assess practical feasibility, technical feasibility and safety of a computational approach for programming newly implanted STN-DBS patients with PD. This computational approach will be based on patient-specific sweet…
Intra-arterial pressure measurements are currently the most promising tool to guide clinical decision making in patients with suspected CMI. Implementation of pressure measurements could result in major improvements in quality of life by tailoring…
To evaluate the efficacy of a new tumor-agnostic ctDNA assay, the ctDNA estimator, to detect newly developing tumors in Lynch carriers.
To determine the proportion of travelers and migrants diagnosed with chronic schistosomiasis as per each centre*s routine assessment, who have active infection at presentation (as assessed and classified by composite reference standards integrating…
Primary objective:The aim of this study is to investigate the number of children using a bicycle helmet after visiting the emergency department (ED) following a bicycle accident compared to children who have not.Secondary objective:The secondary…
Primary objective is to investigate if the sEMG signal derived from the SERA device has an association with weaning failure, defined as an unsuccessful SBT, or extubation failure, defined as the need for re-intubation for respiratory reasons within…
The general objective is to validate a new non-invasive retinal imaging tool that allows the identification of relevant biomarkers in the retina in degenerative diseases of the brain and the eye by scattering and absorption properties.
Optimization of OE-MRI protocols and workflows to prepare for hypoxia mapping and quantification on an MR-linac
The objective is to initiate a hiPSC-resource from 10 genotyped participants of the Doetinchem Cohort Study, with a characterized life course history of up to 35 years during their adult life, with the intent to deploy mechanistic and causality…
Primary RQ: 1) Is time spent in daylight associated with better mood in recently remitted depression patients? Secondary RQ*s: 2) Is the association dependent on age, sex, circadian rhythms and chronotype? 3) Is the association dependent on timing…
We have preliminary data from blood collected in other studies that indeed measuring blood microbiomes is more informative as sampling the corresponding faeces samples and we have built a bio-informatical pipeline that apparently allows its analysis…
The primary objective of the study is to determine the technical feasibility of ctDNA detection in small volumes of capillary blood. This will be investigated through determining the agreement between ctDNA measurements in venous (standard blood…
To evaluate if balloon pulmonary angioplasty (BPA) is non-inferior to pulmonary endarterectomy (PEA) in patients with chronic thromboembolic pulmonary hypertension (CTEPH) who are eligible for both treatments.