154 results
1) to examine adolescents' neural responses to inclusion and exclusion by peers, in relation to the social status of participants and peers. 2) to investigate the neural correlates of the development of self-control, and individual differences…
To demonstrate that CLT is more sensitive for keratoconus detection compared to other corneal topography methods.
To describe the pharmacokinetic profile of a 24 hour infusion of levosimendan and its active metabolites in children with acute or chronic heart failure.
To evaluate the effect on sleep and ptsd of the drug Doxazosin Retard in patients with PTSD who also have sleep problems.
Primary• To assess the safety profile and determine the pediatric maximum tolerated dose and/or recommended phase 2 dose of brentuximab vedotin• To assess the pharmacokinetics of brentuximab vedotin• To determine the overall response rate (complete…
Primary Objective:To evaluate the efficacy and safety of solifenacin succinate o.d. in children and adolescents with OABSecondary Objective:To perform population pharmacokinetics after multiple-dose administration.
What is the prevalence of depression and anxiety in children with asthma. Is this more frequent in asthma than in other chronic conditions like diabetes and Coelikie? And how compares this to healthy children in the same phase of life?
See page 9Primary Objective:The primary objective of this study is to explore the relationship between MPH and academic activity and the mediating roles of ADHD behaviours, cognitive deficits and motivational deficits in this relationship. Therefore…
To investigate whether patients with VLCADD have a different energy metabolism compared to healthy controls.
To evaluate neurologic- and cognitive disorders, neuroimaging and ophthalmological alterations in perinatally HIV-infected children in comparison to matched (with respect to age, sex, race, home environment and socio-economic status) healthy…
Objective: To analyze in more detail the complement activation and regulation and especially the functional CFH activity following three types of interventions in patients known with HUS and correlate these to clinical findings. The three…
The aim of this project is to validate the hypothesis that intranasal insulin improves development and behaviour in children with Phelan-McDermid syndrome.
To define the relation between CsA exposure and occurrence of acute Graft-versus-Host disease. To investigate the relation between CsA exposure and other clinical outcome parameters (engraftment, relapse, treatment related toxicity and survival). To…
To investigate the cross-cultural validity of the Dutch version of the following questionnaires that identify the adolescent*s level of functioning with chronic pain:1. Child Activity Limitations Interview (CALI) 2. Bath Adolescent Pain…
The primary objective of the study is to evaluate whether the addition of LABA to ICS therapy (FSC) is non-inferior to ICS therapy alone (FP) in terms of the risk of serious asthma related events (asthma-related hospitalization, endotracheal…
1. To assess the prevalence of structural, and dysmorphological abnormalities in a cohort of patients with gastroschisis.2. To identify possible candidate genes for gastroschisis by analysing the genes involved in copy number abnormalities in…
The primary aim of the study is to investigate the feasibility of a RCT study on effectivity and workingmechanisms of HRT in children with CP. The Doel van deze studie is ten eerste de feasiblity onderzoeken van een toekomstige RCT study over het…
Gain insight in the anatomy and organisation of the sacral plexus in children with NB and congenital spinal or sacral anomalies. Possible findings can be compared with the results of the healthy subjects, in order to be able to relate findings to…
I. To evaluate what the impact is of posterior scoliosis correction on respiratory muscle function (strength, endurance, power and work of breathing).II. To evaluate the relation of changes in respiratory muscle function, due to the posterior…
Extent the current instrument for assessing autism in deafblind individuals with profound intellectual disability by Hoevenaars-van den Boom et al. (2008; 2009) to a protocol with manual for assessing autism in people with visual impairments, less…