258 results
In breast-conserving surgery, there is evidence that approximately 30% of women receive a suboptimal or poor aesthetic outcome; however there is currently no standardised method of identifying these women.The PICTURE project aims to address these…
Changes in the Fibtem measurements during the first 24 hours after the start of the operation.
Primary Objective: Using fMRI to assess differences in brain activation during: (a) up- and down-regulation of emotional reaction to negative and positive pictures vs neutral pictures; and (b) working memory at low and high load with emotional…
Our projects aim to identify (a combination of) putative diagnostics markers for Alzheimer's disease that allow for accurate discrimination and at the same time can be more readily implemented than the currently available markers, i.e. cheaper…
1. To assess the effects of 3 months neoadjuvant androgen ablation with enzalutamide on the surgicial margin status of men with non-metastasized prostate cancer.2. To properly evaluate the effects of androgen ablation on gene expression, analyses of…
The main objective of this study is to measure executive functions at two levels. First we will compare the results of neuropsychological testing in elderly with autism and compare these findings to elderly without autism. Secondly we will compare…
The purpose of this study is to develop a sleep self-report instrument for people with a mild intellectual disability (SSR-ID) and to assess construct validity of the SSR-ID by showing its association with sleep parameters measured by actigraphy.
The main objective of this study is to investigate the effect of a single tDCS session in children with mild CP on different motor tasks. The second objective is to identify the optimal site of stimulation. In tDCS research the electrodes can be…
To detect ophthalmic differences between patients and controles. To detect (early) changes in the retina in (pre)symptomatic HCHWA-D disease carriers, in order to find a *biomarker* for disease stage and progression.
The objectification of the most effective surgical treatment, in which three operationprocedures are compared.
Objective: This study will investigate if AIM can be trained among people with chronic anger management processes. According to the AIM model, repeating avoidance responses to threatening stimuli may reduce aggressive impulses within this population…
The objective of ths study is to investigate whether use of Tranylcypromine, a monoamine oxidase inhibitor, results in increased expression of HbF in adults. If this is the case, we will use the results of this study to design follow-up research…
Objective: The main objective is to evaluate the effectiveness of the POPP-treatment program in reduction of severity of post-traumatic stress symptoms for sexually abused preschoolers. Secondary objectives are to evaluate the effectiveness of the…
Primary Objective:• Intracardiac blood total flow and maximum flow velocity measured by 4D MR, and compared with 2D MR.Secondary Objective(s):• Intracardiac pressures as assessed by 4D MR , compared with 2D MR, invasive catheterization and…
The primary objective of this study is to evaluate the ability of PET-MRI ( PET, DWI and DCE-MRI) to detect and locally stage breast cancer in patients.
The purpose of this study is to evaluate the effect of PRRT with 177Lu-octreotate on circulating NET transcriptomes. In particular, the variation of circulating NEN transcripts will be correlated to the response to PRRT to test whether this analysis…
The primary objective of the study is to evaluate the effects of orally administered metformin on the immune and metabolic responses of stimulated peripheral blood mononuclear cells (PBMC*s) and macrophages from healthy individuals.
Evaluation of the accuracy of the sentinel node procedure in bladder cancer patients.
The first objective is to assess the effect of age and anxiety disorder on use and effectiveness of emotion regulation strategies in circumscribed vs. complex daily life situations. The second objective is to assess the effect of treatment of…
The PICTURE project aims to address these issues by providing objective tools, tailored to the individual patient, to predict the aesthetic outcome of local treatment. Using a combination of 3D photography and routinely acquired radiological images…