1363 results
Primary Efficacy Objective The primary efficacy objective is to determine the long-term efficacy of NCAP (Neurostimulation of the Cholinergic Anti-inflammatory Pathway) delivered by the implanted device as assessed by the Crohn*s Disease Activity…
The main objective is to assess hallmarks of protective and waning immunity to vaccine preventable and non-preventable viral and bacterial diseases.in cases of various age groups and age-matched healthy controls. Secondary objectives are 1) to…
The current project aims to investigate the efficacy of a new form of treatment that integrates ACT in the daily-lives of ARMS individuals using a small digital device (PsyMate®). We hypothesise the ARMS and FEP individuals who receive the…
Primary objectiveThe primary objective is to evaluate the effect of Pirfenidone on the change in FEV1 over 6 months in lung transplant recipients with BOS, who are treated with Azithromycin.Secondary objectives The secondary objectives involve the…
The aim of the proposed study is to obtain insight into the temporal dynamics of functional reorganization and cognition, and to assess the effect of cognitive rehabilitation on this adaptive mechanism and cognitive functioning.
The primary objective of this study is to evaluate differences in motor evoked potential (MEP) and TMS evoked potential (TEP) to paired pulse TMS between epilepsy patients with a successful response to AEDs and those who do not (refractory patients…
The proposed research intends to gather data to validate the hypothesis that using Nitrox to decompress during Heliox diving will significantly decrease the time and equipment requirements for decompression while being as safe as the standard heliox…
To compare two internationally widely used IVF culture media, the sequential culture medium G5 (G1.5 for culture on day 1-3 and G2.5 for day 4-6) from Vitrolife (Sweden) and a single step Continuous Single Culture Medium (CSCM) from Irvine (Ireland…
To investigate whether using the ARC during 166Ho-RE increases the post-treatment tumor to non-tumor (T/N) activity concentration ratio, compared to using a standard end-hole microcatheter.
The overall aim is develop a rational dosing regimen of liposomal amphotericin B in obese patients. To achieve this goal we have defined the following objectives: Primary objective:* To determine the pharmacokinetics of liposomal amphotericin B…
With this study we aim to elucidate the effects of HBOT on the oral microcirculation in patients with malignant disease in the head and neck region after receiving radiotherapy (RT). We want to test the hypothesis that HBOT improves RT-induced…
To assess the optimal ablation duration using the second generation cryoballoon for isolation of pulmonary veins in the treatment of atrial fibrillation.
In this research study we compare two approaches that can be used to give breathing support to prematurely born babies. Both techniques are currently used in different countries over the world. However, at this moment we don*t know which methods is…
The primary objective is to identify molecular signatures that can serve as diagnostic and/or severity-of-disease markers for PsA and markers that can predict treatment response in patients with PsA. The secondary objective is to elucidate the…
Study Purpose* To continue the evaluation of the safety and efficacy of prophylaxis with BAX 855 for the prevention and treatment of bleeding episodes in PTPs (children and adults from 0 to 75 years of age) with severe hemophilia A.Primary…
Primary objectives are:1) To evaluate the efficacy of Xyrem (sodium oxybate) oral solution in the treatment of cataplexy in pediatric subjects with narcolepsy2) To evaluate the safety of Xyrem in the treatment of cataplexy in pediatric subjects with…
To investigate the feasibility of a 10 week (maximum) gait training with DFES in rehabilitation starting in the sub-acute phase after stroke and the initial efficacy on the recovery of spatiotemporal parameters, gait kinetics and kinematics,…
Study BP29541 is a first in-human, open-label, multicenter, dose-escalation Phase I clinical study of single-agent RO6958688. The study will be conducted in two parts. Part I of the study is single ascending dose in single patient cohorts to…
To assess the efficacy of the novel kit for the detection of PAMG-1 in the cervico-vaginal secretions of pregnant women with clinically intact membranes presenting with signs and symptoms of PTL in predicting time-to-delivery.
The primary objective of the main non-inferiority study is to determine the safety of TACmono starting nine months after kidney transplantation in immunologically low-risk patients in terms of BPAR-rate 15 months after transplantation compared to…