193 results
Primary Objective: To assess the hemodynamical effects of administration of AS in FGR fetuses and to compare these effects with those that occur in appropriate for gestational age (AGA) fetuses. Secondary Objective(s): To investigate the effect of…
Primary objective To evaluate the Overall Response Rate (CR/PRrate) in patients treated with pembrolizumab for recurrent or progressive PCNSL after MTX-based first-line therapy To evaluate the safety of pembrolizumab in subjects diagnosed with…
To investigate if patient controlled sublingual sufentanil tablets as compared to patient controlled intravenous morphine lead to improved independent mobilization on postoperative day 1 after laparoscopic donor nephrectomy (LDN).
The aims of this study are (1) to determine if ear absorbance can be used to non-invasively measure ICP and (2) to determine if ICP differs between glaucoma patients and controls.
The primary objective of this study is to investigate if exogenously supplied ELABELA can induce MZ twinning in cultured human embryos. This will be done using time-lapse monitoring of donated human embryos that will be treated with synthetic…
Safety:* Evaluate the safety of AVXS-101 through incidence of adverse events (AEs) and/or serious adverse events (SAEs)* Evaluate the safety of AVXS-101 based on the change from baseline in clinical laboratory parametersEfficacy objectives will be…
The primary objective of this study is to investigate if shear-wave elastography and contrast-enhanced ultrasonography can identify those patients most suitable fir an intervention (surgery or endoscopic balloon dilation) and those patients that…
To determine the efficacy of a filter-based depletion of RBC-pathogen complexes by a single apheresis tretatment in patients with sepsis.
Primary objectiveThe primary objective is to assess the organizational and financial feasibility of implementation of the DLAM-treatment programme for T2D patients in primary care. This includes an observational cost-benefit analysis, informing…
Therefore the objective of this study is to test the feasibility of the detection of circulating tumor DNA of a variety of tumors in peripheral blood using a novel detection process.
Relevancy: Groin explorations are regularly performed procedures in vascular surgery. To date, the chosen technique will be either electrocoagulation or the Ligasure, depending on the operator*s preference. It is yet unclear whether the chosen…
To quantify clinical and histological changes of the skin in promoting early wound healing when SVF + PRP injectable is used as treatment in comparison to SVF and PRP alone.
To investigate the effects of oxygen therapy within the first hour on the occurence of oxidative stress biomarkers at different levels of oxygenation (hypoxia, normoxia and hyperoxia).
Objective: The primary objective of this study is to evaluate the pharmacokinetics of midazolam in elderly patients (>70 years) admitted to the ICU.
The primary objective of the study is to qualify an objective semi-quantitative CT scoring system lookingat the correlation between the relative change in the semi-quantitative CT score from baseline to week 6after DIILD diagnosis and the relative…
The primary goal is to investigate whether treatment on the MPU leads to a reduction of 'disruptive behavior' compared to CAU. Secondary goals are: to investigate whether treatment at the MPU influences the costs of care for patients,…
To evaluate DIT treatment outcome and possible predictors of treatment outcome in patients with MUSS To evaluate brain structure and function related to SSD pre-and post treatment.
Objectives: To investigate the effect of a daily sachet of probiotics on vitamin K status for 12 weeks vs placebo.
MOODSTRATIFICATION is a large, multi-center international study supported by the EU. Workpackage 3 aims to establish a proof-of-concept for a succesful therapy-stratification model for use in patients with a moderate to severe depressive episode.…
Whooping cough is very contagious. Earlier research shows that family members of a child with whooping cough are often also infected with the pertussis bacterium. However, not everyone who is infected with the bacterium develops symptoms. In this…