2920 results
Non-invasive localization of the origin of idiopathic ventricular arrhythmias
Therefore the primary objective of this study is to evaluate the effect of twice daily application of topical clindamycin1%/benzoyl peroxide 5% gel compared with the standard treatment with topical clindamycin1% lotion on the frequency of active…
With this study we try to answer the following question:What is the clinical outcome after a corrective osteotomy of a forearm malunion when we virtually plan the correction preoperatively and whether or not use patient-specific guides…
By providing patients and therapists with feedback on these networks we can explore whether and to what extent networks can contribute to personalizing psychological treatment for CCRF.
Primary objectives:To determine the mass balance of drug-related radioactivity following i.v. administration of a single dose of [14C]-OTL0038 in humans.To determine the primary route and mechanism of excretion of drug-related radioactivity…
The aim is to check on current virology values (viral load (HBV DNA) and quantified HBsAg, HBcrAg, HBV RNA) to clarify if a complete return to baseline has occurred or if decreased values are still observable in patients that participated in part B…
The main goal of this study is to evaluate efficacy of a single administration of ATH3G10 in patients presenting with an acute STEMI undergoing PCI.The primary objective is to investigate effects on left ventricular remodelling as measured by the…
The aim of this pilot study is to assess the feasibility of the use of CPAP in the acute phase of stroke in AIS patients. In other words, we want to evaluate if the treatment is tolerated and whether it can be applied as scheduled.
To develop a new personalized assessment and analysis approach for identifying efficacy of self-care interventions (home-experimentation), focusing on food supplement use to reduce fatigue. This novel approach is designed to empower patients in…
Perioperative bleeding in the setting of noncardiac surgery is strongly associated with 30-day cardiovascular complications and mortality. Trial evidence suggests that intravenous TXA reduces perioperative bleeding and transfusion in orthopedic…
Primary objective: To evaluate whether intellectual disability and facial dysmorphology are associated with an increased clinical diagnostic yield of genetic testing among patients with a psychiatric illness.Secondary objective: To investigate the…
To establish preliminary safety and tolerability of single- and multiple-ascending oral doses of MYK 491 in ambulatory patients with stable heart failure with reduced ejection fraction (HFrEF)
This will be an explorative study to examine the value of high-resolution ultrasound (HRUS) of the peripheral nerves in NF1 patients. The primary objective of this study is to determine HRUS abnormalities in a large group of NF1 patients, and to…
The objective of this study is to develop a method whereby reliably can be determined if there are microscopic metastases in the neck lymph nodes of H&N cancer patients. In those patients with "clean" nodes the irradiation can be…
In this study we aim to elucidate the effects of inhibited lcFAO on monocyte phenotype and inflammatory activation.
This study is being conducted to collect additional data to describe the safety and tolerability of multiple cycles of IV administration of fosaprepitant daily for 3 consecutive days, concomitantly with a 5-HT3 antagonist, with or without…
This Phase 2b/3 double-blind, placebo-controlled study will evaluate the safety, tolerability, and effects of livoletide on food-related behaviors in patients with Prader-Willi Syndrome (PWS).
The primary objective is to compare, in healthy subjects, the injection site experience of a single dose of 0.25 mg semaglutide sc, given as the DV3396 product to that of the PDS290 product.
Primary objective: To obtain insight into signature of immune responses triggered by a bivalent- or nonavalent HPV vaccination (three-dose schedule). Secondary objectives: To determine the most informative time-points to study different innate and…
To assess the efficacy of LEX0 on the calf for Restless Legs (RLS)