158 results
To determine the (cost)-effectiveness of home-based hypnotherapy by self-exercises added to usual care (UC) of general practitioners (GPs) compared with UC of GPs alone in children with FAP or IBS.
To quantify the role of different abnormal loading conditions on atrial and ventricular electropathology in paediatric patients with CHD.
The primary objective of this study is to validate the *Hearing and Sound* questionnaire, developed by *VeiligheidNL*, which addresses exposure to noise through headphone use and visiting events with amplified music. The main study endpoint is to…
To determine the clinical value of ultrasound, in addition to other non-invasive parameters of disease activity in children aged 3-18 with Crohn*s Disease.
The objective is to examine how working memory functioning in children with ADHD and/or ASD as measured with the Lion game and the Monkey is influenced by context and to assess the diagnostic utility and ecological validity of the Lion and Monkey…
To investigate differences in liking of e-liquid odors between adult smokers, young adult non-smokers, and youth non-smokers
The purpose of this study is to provide remdesivir (RDV) to participants with moderate COVID-19. The primary objective of this study is as follows: To evaluate the efficacy of 2 remdesivir (RDV) regimens compared to standard of care (SOC), with…
The primary objective of this study is to evaluate the long-term safety and tolerability of OV101 in individuals with AS assessed by the incidence and severity of AEs and SAEs in subjects who are at least 2 years old.The secondary objectives of this…
The overall goal of this study is to get an up-to-date data on the incidence, disease burden, and etiology of gastrointestinal infections in the general practitioner population. More specific goals:1. Determine the incidence of gastrointestinal…
Primary Objectives: To evaluate the status of the circadian rhythm of critically ill children in multiple facets and on multiple moments during their PICU stay. To describe the distributions of rhythmic parameters in the paediatric ICU and their…
In this study, the objective is to examine the effect of protocolled cognitive behavioural therapy for insomnia (CBT-I) in adolescents with complex psychiatric problems and sleeping problems (problems falling asleep, staying asleep and/or waking up…
To determine the differences in muscular activity of the diaphragm between children with controlled asthma, uncontrolled asthma, dysfunctional breathing patterns and healthy children.
To determine the efficacy of subcutaneous administration of brodalumab compared with placebo in treating adolescents with moderate-to-severe plaque psoriasis.
To determine the feasibility of using ICG to optically guide the surgeon to the SLN of paediatric melanoma and sarcoma patients. The SNP is a diagnostic procedure.
The aim of this study is to assess the feasibility and efficacy of respiratory muscle training (RMT) in patients with SMA and respiratory muscle weakness.
To determine whether metabolic imaging at 7 Tesla is feasible and suitable to detect changes in phospholipids and APT levels in paediatric brain tumours.
This study has been transitioned to CTIS with ID 2024-514917-36-00 check the CTIS register for the current data. PRIMARY OBJECTIVES*Rx-induction: Comparison of the 3 year EFS rate of 2 induction regimens, GPOH and RAPID COJEC, in patients with high-…
* To test the hypothesis that clonazepam administration has acute beneficial effects compared to placebo on body sway, adaptive tracking, smooth eye pursuit, tapping frequency and the animal fluency test.* To test the hypothesis that multiple-doses…
To evaluate the effect of elexacaftor (ELX)/tezacaftor (TEZ)/ivacaftor (IVA) on glucose tolerance in CF subjects with impaired glucose tolerance (IGT) or CF related diabetes (CFRD)
Main Objectives: To collect clinical data and biological samples derived from blood (plasma, serum, cells and DNA) as well as urine and stool to perform multi-omic and functional biological assays. The resulting data will be integrated and analyzed…