2919 results
To establish the performance of the TouchCare Nano 14 CGM system among persons with DM.
This study has been transitioned to CTIS with ID 2024-515417-17-00 check the CTIS register for the current data. The main objective of this trial is to investigate glucagon receptor occupancy of BI 456906 in the liver with PET imaging using the…
This study has been transitioned to CTIS with ID 2024-518838-82-00 check the CTIS register for the current data. To evaluate if a combination of FAPI-PET/CT and FDG-PET/CT scan is able to detect active fibroblast tissue and inflammation in patients…
Primary safety objective: The primary safety objective of the study is to assess the safety of the Apreo Endobronchial System for treatment of severe emphysema.
The objective in the vanguard phase of the LIMIT trial is to assess the feasibility of recruiting 400 subjects over approximately 3 years at 5 centres. The objectives in the full trial are to evaluate the safety and efficacy of a common, lower INR…
This study has been transitioned to CTIS with ID 2024-517805-10-01 check the CTIS register for the current data. We aim to investigate whether sodium oxybate can be used as a novel treatment in psychiatric patients with catatonia. Our primary…
The purpose of the study is to provide comparative analysis of breast imaging modalities of BCT (nu:view) compared to MRI.
This study has two parts. The main objective of part 1 (in vivo) is todetermine changes in markers of oxidative stress in exhaled breath as a result of different short term oxygenation strategies (liberal versus conservative) . The main objective of…
This study has been transitioned to CTIS with ID 2024-518065-10-00 check the CTIS register for the current data. The aim of the study is to demonstrate that HAI P chemotherapy is an effective treatment for unresectable intrahepatic…
The main objective of this proposal is to establish ex-vivo models of bronchial epithelial cells from children. Use of (1) epithelial organoid cultures derived from bronchial or nasal epithelial cells; and of (2) bronchial brushings; (3) nasal…
To test the hypotheses that patients who show severe fatigue after COVID-19 infection exhibit an exaggerated abnormal expression of inflammatory monocyte genes (particularly of the genes involved in pyroptosis, such as IL-1 and IL-6) as compared to…
The primary goal is to assess the survival rate of dental implants placed in cleft patients compared to non-cleft patients. Secondary objectives will be: evaluation of the parameters on the survival of dental implants (smoking, oral hygiene, length…
To determine the factors that contribute to response to CAR T-cell therapy, both at the tumour-end, as well as on the T-cell side to understand mechanisms of efficacy and immune escape in order to optimize this treatment and to reduce toxicity
The objective of this study is to collect additional data on the performance and safety of the slowly-resorbable TIGR® mesh of incisional hernia prevention in patients with AAA undergoing midline laparotomy.
To determine the diagnostic performance (sensitivity, specificity, and area under the ROC curve) of the current eye-movement based perimetry techniques, SONDA and BulbiCAM, as potential screening instruments for glaucomatous VF defects in ophthalmic…
This project has the following objectives: 1) to determine the effect of vertical, horizontal and mediolateral supportive forces of the RYSEN on gait parameters and muscle activity in able bodied individuals and patients; 2) determine the…
The ultimate goal of the consortium is to use state-of-the-art imaging, genetics, and machine-learning techniques to identify NCCM patients at risk for severe arrhythmia or stroke and guide preventive therapy using personalized risk scores
Objective of the study is to investigate if a mild sensitizing drug (oral capecitabine) combined with a high dose hypofractionated radiation regime to the esophageal region is feasible in this unfit patient group. If feasible, in a consecutive study…
Determine the safety (oncologica! outcome and toxicity) of an comprehensive treatment combining recent advances in the treatmentof high risk prostate cancer.