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Research on new imaging technique for personalized breast cancer treatment (BREAST4D)

Part A: Determine the performance of using 4D DCE-BCT for tumour staging. Part B: Determine the performance of 4D DCE-BCT in monitoring of treatment response and prediction of final treatment outcome based on early response in patients that undergo…

Less Is More: Optimized pharmacotherapy with improved coNtinuity of CarE in hospitaLized oLder peOple

The LIMONCELLO study aims to assess the effect and cost-effectiveness of TMPC compared to usual care.

Comparison Of reduced DAPT followed by P2Y12 inhibitor Monotherapy with Prasugrel vs stAndard Regimen in STEMI patients treated with OCT-guided vs aNgio-guided completE revascularization.

This study has been transitioned to CTIS with ID 2024-515883-30-00 check the CTIS register for the current data. The primary objective of this study is to prove noninferiority regarding safety and effectiveness of 30-45 day of DAPT followed by…

The effectiveness of Cerclage for the reduction of extreme preterm birth and
perinatal mortality in Twin pregnancies with a short cervix.

To assess the effectiveness of a cerclage in women with a twin pregnancy with a midpregnancy short cervix compared to standard treatment (no cerclage) in the prevention of extreme preterm birth (PTB) < 28 weeks of GA.

NEW characterizing rate of progression in USHer syndrome (NEW-USH) study
a natural history study in patients with Usher syndrome

The study will help us to determine 1. the necessary type of (combined) examinations and 2. the sample size that is essential to evaluate (future) genetic therapy in Usher syndrome type 2 and USH2A associated nsRP.

Clinical outcomes and cost-effectiveness of a diagnostic and treatment strategy of upfront CTCA plus selective non-invasive functional imaging compared with standard care in patients with chest pain and suspected coronary artery disease

This strategy will result in a reduction reduce the incidence of major adverse cardiovascular events (MACE) defined as death or non-fatal myocardial infarction and appear more efficient than care as usual.

Multifactorial eye diseases

The purpose of this protocol amendment is to meet the current and future needs of the MacTel Project’s collaborating investigators and continue meeting initial objectives. In addition, a third objective is to understand the mechanisms involved in…

Glyaderm in Pediatric Burns

The aim of this study is to describe the scar quality in a paediatric burn population treated with Glyaderm up to 12 months after surgery.

Immunity against neoantigens in CMMRD

In this explorative study, we aim to: Analyze neoantigens expressed on different tumors of CMMRD patients, to identify more possible target antigens for DC vaccination studies and to select the antigens that are most frequent. …

FITFOOD

This project aims to improve physical performance in older patients, by offering a personalized combined nutritional intervention with a physical activity training program. The intervention starts at hospita! admittance, and is continued after…

PRE- MISTIC: MRI and cine Imaging to Improve Staging of Tumors In the Colon.

The objective of this study is to pilot the feasibility of MRI and cine imaging in improving pre-operative staging of colon tumors. The specific aims of this pilot study are to establish an optimized scanning protocol and provide preliminary…

BIgAN II

We want to remap the entire bacterial ecosystem in the gastrointestinal tract of patients with lgA nephropathy after a period of roughy two years, in order to gain insight into the processes that may play a role in the development and progression…

TransMind

This mixed-methods pilot study will explore the effects of a group-based MBI on body and emotional awareness in TGD individuals by collecting both quantitative measures and qualitative experiences on an adapted gender-inclusive MBI program.&…