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PARASOL

Primary objectives: - To examine how environmental exposures influence the prevalence, 5-year incidence and progression of cardiometabolic and chronic respiratory disease in the general population. - To determine the mediation effect of lifestyle…

Less Is More: Optimized pharmacotherapy with improved coNtinuity of CarE in hospitaLized oLder peOple

The LIMONCELLO study aims to assess the effect and cost-effectiveness of TMPC compared to usual care.

The effect of exeRcise And Diet on quality of life in patients with Incurable Cancer of Esophagus and Stomach

The aim of the RADICES study is to investigate the effects of a 12-week exercise and nutrition intervention for patients with metastatic oesophageal or gastric cancer. The intervention will be completely tailored to the condition and nutritional…

PreventPAP trial

To compare postamputation pain (phantom limb pain and residual limb pain) one year postoperatively in patients receiving a lower extremity amputation with standard neurectomy versus those who received targeted muscle reinnervation.

Re-evaluation of the muscle-full effect during continuously elevated amino acid availability in healthy young males

To assess muscle protein synthesis rates to continuous, elevated plasma amino acid availability in healthy young males

The effect of AlgaSense® on the stress response and mental wellbeing in young adults: The Stress Examination: Relief Effects with Nutritional AlgaSense® (SERENAL) study

The aim of the present study is to investigate the effect of a microalgae (Hematoccocus pluvialis) on the stress response and mental wellbeing in jong adults.

Clinical outcomes and cost-effectiveness of a diagnostic and treatment strategy of upfront CTCA plus selective non-invasive functional imaging compared with standard care in patients with chest pain and suspected coronary artery disease

This strategy will result in a reduction reduce the incidence of major adverse cardiovascular events (MACE) defined as death or non-fatal myocardial infarction and appear more efficient than care as usual.

Early detection of symptoms using digital patient-reported symptom monitoring and a Fitbit to optimize care in metastatic breast cancer (SYMPHA, BOOG 2024-01).

This study aims to determine the effect of real-time symptom monitoring on HRQoL in patients with mBC who start first-line chemo(immune)therapy. Further objectives include analyzing the effect of PRS monitoring on physical functioning, the severity…

Meaningful digital biomarkers for longitudinal monitoring of obstructive sleep apnea around diagnosis and during titration of treatment with CPAP or MAD

Primary Objective: Assess which digital health metrics are relevant to monitor for patients with (or highly suspected of having) obstructive sleep apnea before and after diagnosis, and during titration of treatment with continuous positive airway…

Targeted PRECIsion NUTrition strategy to prevent chronic metabolic diseases

Our study aims to identify unique Metabotypes among individuals with overweight at risk of T2DM and assess their response to a 1-year precision dietary macronutrient modulation. The objective is to provide proof-of-concept that this approach…