1929 results
Primary objective- To assess the effects of Org 25935 on heavy drinking in subjects with alcohol dependence.Secondary objectives- assess the effects of Org 25935 on the amount of drinking- To assess the effects of Org 25935 on the first relapse to…
Human intestinal biopsies will be used to further develop an in vitro intestinal model. This model will the be used for future research to study the effect of nutreints and drugs on intestinal function. The human biopsies will be compared with…
Primary goal:To investigate whether specific plaque characteristics are associated with ischemic lesions, especially (clinically silent) cerebral micro-infarcts, we will perform preoperative high resolution 3 and 7 Tesla MR plaque imaging in…
The aim of the proposed research is to test, by the use of functional magnetic resonance imaging, the hypothesis that psychometric schizotypy (referring to, e.g., subclinical hallucinations in healthy people) is associated with reduced activation of…
The main objective is to gain insight into the effects of guided imagery on pain, self efficacy and functional status of people with fibromyalgia and into the relationships between these outcome variables.
To compare the success rate and the occurrence of complications of re-crossectomy and (repeated) UGFS for the treatment of recurrence of the SSV for a period of 5 years.
Is the present malrotation of the tibia, 15 degrees exorotation and 10 degrees endorotation, after intramedullary nailing acceptabel. Furthermore, we want to know which technique could reduce the possible malalignment in patients. In present there…
In deze studie zal de nauwkeurigheid van peroperatieve meting van de cuppositie door een nieuw ontworpen, onlangs gepatenteerd, meetinstrument worden onderzocht. In de toekomst kan, indien het meetinstrument betrouwbaar blijkt, peroperatief de…
The purpose of this clinical study is to provide confirmation of the clinical safety and performance of the CINCOR* System in patients at risk of developing CIN who are undergoing interventional percutaneous coronary procedures.Further, the data…
The objective of this study is to optimize the diagnostic strategy of atrial fibrillation in patients with stroke or TIA. There is no evidence-based guideline to diagnose AF in patients who have had a stroke or TIA. An objevtive related to this…
How friendly is Delta-dry to the skin versus regular padding?Will Delta-dry be more functional than regular padding in patient experience? (Functional as in daily activity's concentrated to getting wet of the cast) How is the processability of…
The objectives of the study are:Developing an experimental design to obtain empirical data about the effects of a drama intervention on anxiety and mood disorders of adolescents.
Primary objectives: (1) Evaluation of the efficacy of vaccination against HPV 16, 18, 6 and 11 followed by local applications of imiquimod 5% cream compared to treatment with imiquimod alone for usual type VIN, (2) evaluation of the systemic and…
Primary Objective: To determine the sensitivity and specificity of MRI in a consecutive series of adult patients suspected for acute appendicitisSecondary Objective(s): Is MRI of additional value in adult patients with inconclusive US? And is…
The minimal duration of an effective distraction period has not yet been determined. In the past, two months distraction showed comparable results with three month distraction. In this study, we would like to analyse the effectivity of a one month…
The current study is designed to test the hypothesis that the medulla in transplanted kidneys is still hypoxic at 1 day after transplantation using a non-invasive method: BOLD MRI.By studying two groups a comparison can be made between patients…
The primary objective is to investigate if the use of the Online Exercise Coach enhances compliance with the follow-up exercise program. Therefore the primary objective is: 1. Are patients who used the OEC during their follow-up exercise treatment…
In a small pilot study to investigate possible occurence of blood chemistry deviations and / or a tamponade after the application of ACF-Matrix haemostat in the (L)IMA bed.
Primary Objective:To preliminarily evaluate the efficacy of GLPG0259 compared with placebo in terms of the proportion of subjects achieving ACR20 at Week 12 (Visit [V]7).Secondary Objectives:•To evaluate the efficacy of GLPG0259 compared with…
The primary objective of this study is to compare the progression free survival (PFS) following administration of IPI-504 plus best supportive care versus placebo plus best supportive care in patients with metastatic and/or unresectable…