8986 results
We have recently implemented ultrarapid genetic testing using Nanopore long-read genome sequencing (LR-GS) at Erasmus MC to guide treatment and enhance outcomes in urgent care scenarios. In this study, we aim to retrospectively…
This mixed-methods pilot study will explore the effects of a group-based MBI on body and emotional awareness in TGD individuals by collecting both quantitative measures and qualitative experiences on an adapted gender-inclusive MBI program.&…
The REPLACE study aims to determine whether not changing the catheter (catheter retained) for catheter-associated urinary tract infections (CAUTI)affects the recurrence-risk of CAUTI.
To evaluate the efficacy of a new tumor-agnostic ctDNA assay, the ctDNA estimator, to detect newly developing tumors in Lynch carriers.
The primary objective of this multicenter, observational study is to determine the incidence of chronic opioid use 30 days and 3 months after an initial opioid prescription at ED discharge. Secondary objectives include assessing the incidence of…
The aim of this study is to investigate whether the social categorization process based on the patient’s gender (within this study only subdivided into cis-men and cis-women) affects the clinical evaluation, treatment of hyposexual sexual desire…
Through a randomized-controlled trial, we aim to investigate the effect of a growth mindset intervention for children with dyslexia on the effectiveness of their dyslexia treatment. Our primary hypothesis is that children who have received the…
The aim of this trial is to investigate the safety and efficacy of an adaptive anastomosis using the C-REX RectoAid Cath following elective anterior resection for sigmoid or proximal rectal cancer, or premalignant lesions not amenable tot endoscopic…
The primary objective of the study is to investigate the medium to long term effects of replacing the conventional CXR exam with an ultra-low-dose CT in terms of patient health.Secondary outcomes are measures are • Quantity and type of follow-up…
To acquire metabolic health data from three dietary challenge meals for thedevelopment of an algorithm for personalised dietary advice, and subsequentlytest the effectiveness of this personalised dietary advice compared to ageneral healthy diet…
The primary objective of this study is to evaluate the clinical performance of the [Redacted] PD-L1 [Redacted] CDx Assay in terms of its ability to identify patients with non-squamous metastatic NSCLC (mNSCLC) who may benefit from treatment with […
Our study aims to identify unique Metabotypes among individuals with overweight at risk of T2DM and assess their response to a 1-year precision dietary macronutrient modulation. The objective is to provide proof-of-concept that this approach…
The primary objective of this pilot study is to examine the impact of MNS on cardiac electrophysiology measured at a high-resolution scale during SR.
To assess the impact of using breathing instructions while performing motion-compensated MR imaging of lesions in the thorax or abdomen aimed at radiotherapy treatment planning as compared to motion-compensated scans without instructions and free-…
To predict the progression of CKD with diuretic testing.
The primary objective of this explorative study is to investigate the effect of 3-month preparation period of regular walking exercise prior to the Nijmegen 4-Day marches on objectively measured AF burden (primary parameter), self-reported AF burden…
The main objective of this study is to observe current AE treatment strategies and the treatment response of these strategies after 2 weeks in several hospitals. Secondary objectives are (1) to measure effect treatment on FeNO, eosinophils and…
The purpose of the VISABL-AFL study is to demonstrate safety and efficacy of RF ablation of type I atrial flutter (AFL) with the Vision-MR Ablation Catheter 2.0 in conjunction with the Osypka HAT 500 RF generator and irrigation pump. Data collected…
Primary objective: To establish a controlled human infection model for C. difficile which is safe, well tolerated and results in microbiological and clinical endpoint in ideally >=70% of volunteers. Secondary objectives:- Assess colonisation…
To develop a 5 fraction de-escalated dose SBRT protocol potentially capable of reducing side effects intended for prostate cancer patients with empty bladder