511 results
Primary:To evaluate the safety of a single subcutaneous injection of ISIS 325568 administered at four increasing dose levels (50, 100, 200, 400 mg/week) and to evaluate the safety and tolerability of multiple doses of ISIS 325568 (three intravenous…
The primary objective of this study is to determine the anti-inflammatory potential of mechanical auricular Vagus nerve stimulation in healthy humans.
The primary objective of the study is to demonstrate that patients with very early arthritis have a higher probability of achieving a state of clinical remission at end of infliximab therapy if treated with infliximab plus MTX when compared to MTX…
The objective of the study is to evaluate the clinical efficacy of 3M* Coban* 2 Layer Compression System in the treatment of venous leg ulcers compared to Rosidal® K shortstretch compression bandage (Lohmann & Rauscher, Rengsdorf, Germany).
The objective of this project is to assess joint mobility of the foot, knee and hip to investigate in more detail the relationship between joint mobility of the lower extremity, plantar pressures and walking capacity in diabetic patients with and…
application of tin foil on an amputated leg deminishes fantoom pain
The major aim of this study is changes in tinnitus loudness (daily report mark) and annoyance (daily report mark) and the duration of this change (time).
The Primary Objective of the study is to dettermine the relative efficacy of AZD2171 [RECENTIN] (both monotherapy or in combination with oral lomustine) compared to oral lomustine alone by assessment of progression free survival (PFS) as assessed by…
The objective is to find out whether injection of Botulinum toxin A into the wall of the bladder has, besides effects on bladder capacity and urgency symptoms, any influence on the contractility of the detrusor muscle.
Objective of this study is to evaluate the amount of shed blood in patients treated with a postoperative retransfusion system. The influence of the position of the drain will be analysed by comparing intra-articular position versus subfascial…
Objective of this first human study with Lu AA24493 is to evaluate the safety, tolerability, immunogenicity and pharmacokinetics of Lu AA 24493 in patients with acute ischemic stroke. In addition patient outcome on National Institutes of Health…
The objective of this study is to determine whether arm function changes after active-movement stimulating (ACTS) training and if so, which mechanisms (neurophysiologic, biomechanic and/or functional domains) are influenced by ACTS training.
To determine the effectiveness of a maintenance treatment by SMS (SMSMT) in overweight and obese children, after a short-term multidisciplinary cognitive behavioural group therapy (CBGT).
Goal of this study is to assess the feasibility of a biodegradable polyurethane foam for closing of oroantral communications. The assessment will take place in a small number of patients. On the long term, the objective is the clinical appliance of…
To compare the Anal Fistula Plug with the fistulotomy in the treatment of low perianal fistula.
Establish the technical feasibility and safety of implantation of the investigational device, adjustment of the investigational device post-implantation and the ability of the investigational device to reduce mitral valve regurgitation.
To assess whether a single shot of dexamethasone reduces postoperative pain, and reduces the time children need to start with drinking and eating.
Objectives:To assess the effect of a single meal replacement (InsuVital®) with or without added leucine on blood levels of insulin, C-peptide and glucose in patients with T2DM.
The objective of the study is to provide access to sunitinib treatment for patients who have completed a prior sunitinib study and are judged by the investigator to have the potential to benefit from sunitinib treatment. During this study the…
Primary: To test the safety and feasibility of autologous MSC therapy in patients with refractory Crohn*s Disease.Secondary:1 To evaluate clinical response in patients with refractory CD upon MSC infusion.2 To assess endoscopic- and histologic…