511 results
The objectives of this study are to gain more insight in the efficacy of splinting therapy for correction of the anatomy and answering the followig questions:1.What are the effects of conservative splinting therapy in children with congenital hand…
Objective: Our goal is to prove that subcuticular sutured wounds will have less discharge than after closure with staples. Secondary outcome is patient satisfaction about wound and wound pain.
To study the impact of 3 day exposure to atorvastatin 80mg on Annexin A5 targeting after ischemic exercise in the non-dominant forearm. This to confirm results from our previous study.
The aim is to evaluate the effectivity of training in mindfulness with patient who underwent a PCI-procedure on different variables: (i) psychological wellbeing (mood, anxiety, depression and quality of life), (ii) clinical relevant physiological…
The primary objective of the trial is to demonstrate non-inferiority of treatment with TMC278 when administered as 75 mg q.d. compared to the control group (EFV) in regard to the proportion of virologic responders (plasma viral load < 50 HIV-…
The purpose of this study is to evaluate the effects of QVA149 300/50, a fixed dose combination of QAB149 300µg and NVA237 50µg, versus placebo and two doses of QAB149 300µg and 600µg, in terms of lung function in patients with moderate to severe…
The primary objectives of this trial are the following:- to determine the dose dependency of the antiviral effect of TMC435350 during 1 week ofmonotherapy in treatment-naïve HCV-infected subjects;- to determine the dose dependency of the antiviral…
To obtain more information about the efficacy and tolerability of AD 923 in long-term management of breakthrough pain in subjects with malignicies who are taking a stable dose of background opioids and receive therapy for BTP.
The primary goal is to find out whether or not you can reach with the new cooling liquid in the Paxman cooler, and probably with air cooling, a ±5°C lower temperature of the scalp skin.The secundary goal is to find out how a possibly reached lower…
To investigate whether therapy with the tyrosine kinase inhibitor Sorafenib will increase the accumulation of radioiodine (RaI) and decrease tumor progression in patients with recurrences or metastases of non-medullary thyroid carcinoma with absent…
Primary objectives:A. To determine the ability of the Toric ARTIFLEX PIOL to reduce astigmatism (performance); B. To establish the mechanical properties of the lens in the anterior chamber in terms of rotational stability of the lens, tilting of the…
To compare the efficacy of fesoterodine to placebo and tolterodine ER in subjects with overactive bladder after 12 weeks of treatment.
1. To decipher the biological basis underlying the alterations in ubiquitination of histones in response to anthracyclines and proteasome inhibitors.2. to find out whether the combined use of anthracyclines and proteasome inhibitors has additive or…
The aim of this study is to determine the quantity of vitamin D3 in anterior adipose tissue in pregnant women, and to determine the influence of exposure to sunlight and the consumption of fatty fish on vitamin D storage in anterior adipose tissue.…
To assess the bile acid composition of cystic bile and serum pharmacokinetics after a 3-week treatment with UDCA and to correlate pharmacokinetic parameter sof UDCA in bile and serum during steady state.To compare the composition of bile acids and…
The effect of yoga on pain and quality of life in children with functional abdominal pain (irritable bowel syndrome, functional dyspepsia, functional abdominal pain syndrome).
OBJECTIVE: It has been estimated that one in nine women will undergo a hysterectomy during lifetime. Up to 10% of these women will subsequently need surgical repair for vaginal vault prolapse thereafter. Sacral colpopexy is a generally applied…
To test the hypothesis that patients who do understand the importance of tolerance of pain to regain motion after a radius fracture, do better than patients who don't understand, in terms of motion and DASH scores at follow-up. Secondarily, to…
The aim of the study is to see if the (psycho)social functioning and the quality of life of forensic psychiatric patients improves when treated according to a forensic CRA-protocol
To compare the effects of intensive resistance training of the lumbal extensors with usual care as provided and prescribed by the GP, for patients with chronic a-specific low back pain.