511 results
The main objective is to find out if dividing the daily oral dose prevents diarrhea without increasing risk of graft failure. Secondary objective is the quality of life and effect on intestinal permeability.
The purpose of this study is to improve, implement and evaluate an intervention program to improve physical activity in daily life and sportsparticipation of adolescents and young adults with MMC. The purpose of the intervention "Active…
.Currently, vacuum-assisted drainage and closed drainage using redon catheters are widely accepted methods for the treatment of mediastinitis. However, it is unknown which technique is considered to be the most effective. We hypothesize that closed…
Primary objective:to study changes in synovial inflammation and cytokine expression in serial biopsy samples following the administration of adalimumab in patients with active rheumatoid arthritis.Secondary objectives: (i) assess clinical response…
Primary outcome is to evaluate whether successful ECV is associated with maternal thyroid function and mood state in single pregnant women with breech position at end term.
The objectives of the present study are twofold:1 screening patients with diabetes type 2 for psychological risk factors and2 studying the effect of a self-management training on metabolic regulation in patients starting with insuline therapy
Aim of the study is to study the influence of GH receptor polymorfisms on the effects of growth hormone substitution in aduts with GH deficiency.
Excision versus PDT in the tratment of Bowen's disease. What's the best therapy on behalve of recurrence rate, cosmetic outcome and cost-utility.
Primary:To identify the recommended dose of sorafenib and of sirolimus for combination therapy in subsequent phase II trials Secondary:1. to determine the safety profile of the combination therapy of sorafenib with sirolimus.2. to determine, if…
To determine the effect of a manualized group treatment for BED patients versus an individualized treatment (tratment as usual) at the GGz-Midden Brabant.
The aim of this study is to compare the new covered TIPS-stent with paracentesis with albumin infusion with regard to nutritional status, quality of life and survival. The theory is that when ascites is treated in an earlier stage of liver cirrhosis…
To show whether an intake of 20g CLA per day has negative effects on liver and kidney function in healthy human volunteers.
In vitro selection of microbiota that can be used in a subsequent trial with children with IMD. The selection will be made based on the cytokine profile and immune cell characterization after co-culture of PBMC*s with bacteria. Influence of human…
To investigate whether treatment with candesartan (ARB) reduce 24-hours systolic BP and aortic stiffness more effectively than treatment with metoprolol (beta-blocker) in patients with repaired CoA and late hypertension.
Evaluate which PEG (4000 or 3350) is most preferred by children.Evaluate whether a preferable taste of the drug can lead to a better compliance and subsequently to a better success percentage of the treatment of childhood constipation.
The aims of the current study are1. to investigate the efficacy and safety of a continuous infusion of 'low dose' danaparoid in patients with acute renal failure needing CRRT2. to investigate whether repeated measurements of anti-Xa levels…
Primary objective: To confirm the safety of the use of Urocell as a treatment for stress incontinence due to intrinsic sphinctre deficiency.Secondary ojectives: - To score the quelity of life with a standardized questionnaire and to score the level…
Studies provide statistically significant evidence of the effectiveness of high-frequency chest wall oscillation administered via The Vest* System.St. Elisabeth Ziekenhuis Tilburg wants to demonstrate the effectiveness of HFCWO on ventilator-…
The primary aim of the study is the prospective recording and follow-up of the clinical and radiographic data of patients who received soft tissue interpositional arthroplasty with Graft Jacket® as a treatment of painful glenohumeral osteoarthritis…
1)to compare the analgesic efficacy of intravenous versus rectal paracetamol as assessed by VAS scores, PCA morphine consumption.2)To assess the pharmacokinetic profile of intravenous and rectal paracetamol by intravenous plasma paracetamol and…