786 results
The main objective of this study is to investigate whether perspective (i.e. first person vs. third person) directly influences the interplay between body ownership and pain perception.
Patients with splanchnic vein thrombosis are at increased risk of recurrent VTE and bleeding. Routine anticoagulation with unfractionated heparin or low molecular weight heparin followed by warfarin is recommended in this setting, but limited data…
The proposed research combines two emerging technologies, Cerenkov Luminescence Imaging (CLI) and Gallium-68 PSMA (68Ga-PSMA), in order to assess surgical margins during prostate cancer surgery. CLI involves imaging of a faint light emitted from…
The BONE LIGHT study aims to demonstrate the superiority of the usage of PBS as an osteosynthesis technique, compared to intra medullary nailing for the treatment of (impending) pathological humeral fractures.
Primary objective: To evaluate effectiveness, directly after intervention, of an individual face to face Managing Fatigue program on participation for people with NMD, including FSHD or MM compared to a control group receiving usual care.Secondary…
Primary objectives: 1. To compare the efficacy of vamorolone administered orally at daily doses of 6.0 mg/kg over a 24-week treatment period vs. placebo in ambulant boys ages 4 to <7 years with DMD; and2. To evaluate the safety and…
To investigate the progression-free survival after radiotherapy to a single lesion in patients with stage IV non-small cell lung cancer who achieved at least stable disease with immune therapy alone or concurrent immune therapy and chemotherapy and…
BEWARE 2.0: body awareness training for wearing-off related distress in Parkinson's disease patients
Do patients that receive the BEWARE training have a higher score on the Chronic Illness Acceptance Questionnaire at the end of treatment (and at 3 month follow-up) compared to the treatment as usual (physical therapy only)?
The purpose of this study is to investigate if there is a difference in the injection site pain experience after an injection under the skin (subcutaneous) with 2 different products, semaglutide and dulaglutide, in healthy volunteers. The 2 products…
To describe the real-world population pharmacokinetics and pharmacodynamics of eculizumab in unselected PNH patients
Primary Hypothesis: - There is a difference in PROMIS Physical Function Upper Extremity Short Form (PROMIS PF UE SF) score between group A (6 weeks distraction) and group B (8 weeks distraction) at 1 year after first carpometacarpal joint…
The aim of this study is to compare pain or discomfort during the ingreep between WALANT and tourniquet use.In addition, we aim to determine whether carpal tunnel release or trigger finger release using WALANT has an effect on recovery, patient-…
The objective of this study is to evaluate the biomechanical effect of the newly developed rocker soles aiming to reduce the mechanical load in patients suffering with Achilles tendinopathy and plantar fasciitis. A secondary objective is to evaluate…
Prone versus supine positioning for rectal cancer irradiation using volumetric modulated arc therapy
The primary aim of the study is to investigate the effect of patient positioning on OARs sparing in rectal cancer patients treated with VMAT (hypothesis 1). The secondary aim of the study is to investigate the possible differences in optimal patient…
The aim of this study is to gauge the feasibility and potential order-of-magnitude the ReHab-TOAT concept may have on improving arm-hand skill performance in both subacute and chronic stroke patients. These data will be used to a) optimize the…
The primary objective of this study is to determine histological ablative efficacy by absence of vital (tumour) cells in the treated prostate zone with (multi)fibre setup in men with PCa scheduled for radical prostatectomy. The secondary objectives…
The aim of this research study is to look at the effects of cheese ingestion at rest and after resistance type exercise training on muscle protein synthesis.
To assess the efficacy of inhaled RVT-1601 in comparison with placebo following 12 weeks of treatment
The primary objective of this study is to compare the overall survival (OS) associated with rAd-IFN, when administered with celecoxib and gemcitabine, versus that associated with celecoxib and gemcitabine alone for the treatment of patients with MPM…
The main objective of our research is to study the effectiveness of the SAFER pregnancy intervention in reducing risk behaviour (i.e. smoking and alcohol use) in pregnant women and women with the wish to conceive. The secondary objectives focus on…