29 results
To compare discrimination ability for touch and temperature between subjects with Down*s syndrome and healthy controls. To compare thermal pain thresholds between subjects with Down*s syndrome and healthy controls
The objective is determine the correlation between the outcome of the cultures of the nasopharyngeal swab, the nose swab, the swab from a handkerchief and the handkerchief.
The primary objective is to assess the feasibility and accuracy of dynamic contrast enhanced MRI in diagnosing UC or CD in children as compared to endoscopy and abdominal ultrasound.The secondary objective is to assess the feasibility of dynamic…
In this research, a small group of children known to suffer from complex febrile seizures (FS) will be studied. An increase in expression of FS1 will be investigated in blood in comparison with an control group. This will be done by isolating FS1…
Research of lung function and exercise capacity in late preterms (32-36 weeks gestation) in comparison with term born controls of 8 years
Primary: To investigate if there is a correlation between findings of transabdominal ultrasound measurement of the rectum and rectal digital examination. Secondary: To investigate if there is a correlation between an enlarged rectum (diameter &…
To investigate if there is a correlation between the peak GH concentrations after ingestion of gelatin protein and the peak GH concentrations after the two standard tests (GHST) in order to discriminate between GHD and non-GHD. To investigate the…
The purpose of this study is to investigate the genotype of a large group of CSNB patients for which the phenotype is already known. We hope to increase our understanding of CSNB in order to improve diagnosis, to offer more realistic prognoses and…
The overall objective of this study is an improvement in (early) diagnosis of NEC and its life-threatening complications, thus to be able to detect children who are *at risk* for NEC and its complications as early as possible. To this end we will as…
The objective is to describe the nature and underlying (neuromuscular en biomechanical) factors of dysphagia in different neuromuscular diseases in relation to different consistencies of food. Identifying the contributing factors are starting points…
The purpose of this study is to characterize in hospitalized children across Europe:• the prevalence of malnutrition on admission and at discharge,• the effects of malnutrition on outcomes, such as length of hospital stay and occurrence of…
First objective is to indicate neurocognitive outcome after mild traumatic brain injury in children. Second objective is to indicate prognostic factors for negative neurocognitive outcome.
1. To determine clinical symptoms of Dientamoeba fragilis infection. 2. To evaluate the efficacy and safety of clioquinol versus metronidazol in the treatment of Dientamoeba fragilis in children.3. To evaluate the duration of positive PCR…
Primary - to determine factors that predict outcome in children with symptomatic heart failure secondary to cardiomyopathy, in order to choose an optimal management strategy for these children. Secondary - to identify predictive factors that can be…
1. To assess reference values of a pre-defined set of biomarkers for AKI in *surgical* infants with normal kidney function.2. To determine the incidence of AKI in critically ill infants, according to pRIFLE criteria.3. To evaluate the sensitivity…
Main objective is to assess CFTR protein expression in nasal epithelial cells and in different peripheral blood immune cell subsets from CF patients with different CFTR gene mutations. Secondary objective is to correlate these expression levels with…
Primary Objectives:To (1) Assess the feasibility and tolerability of performing US and/or contrast-enhanced MRI in children with central venous catheters (CVCs) or peripherally inserted central catheters (PICC lines); (2) assess the accuracy of US…
Primary Objective: Mapping the consequences of a congenital monokidney on kidney function for children with MCKD.Secondary Objective(s): - Giving recommendations about follow-up for children treated with nephrectomy for MCKD.- Defining better blood…
Primary objective:-To diagnose acute pyelonefritis with MRI in comparison with the reference standard: DMSA scanning.Secondary objectives:- To determine whether MR-diffusion weighted imaging (DWI) has additional value in the imaging of…
To assess the (additional) diagnostic value of faecal calprotectin in children, age 4-18 years, with symptoms suggestive for IBD, in a primary and secondary/tertiary care setting.