195 results
The project has three main scientific objectives: (1) To investigate how speech processing with CIs affects listeners* mental representations at lexical and sub-lexical levels, as well as the flow of information between these levels; (2) To study…
The primary objective of the proposed study is to examine the neural substrate of cognitive and social-emotional apathy in patients with schizophrenia. Secondary, we intend to explore the concentration of brain metabolites and structural differences…
To validate spectral analysis of the fHRV as a new method for fetal monitoring. To determine the exact influence on fHRV of several commonly used medicines in obstetric care; namely tocolytic drugs, corticosteroids, antihypertensive agents,…
The present study has 1 primary and 1 secondary objective:1: The primary objective of the present study is to analyse the effects of supplementation with ITFs of different chain lengths and RSC on hepatitis B vaccination efficacy. The main parameter…
Are Alphabodies against IL23 effecive in the transplant model of psoriasis
The primary objective of this study is to demonstrate that free field word recognition scores in quiet and noise with CI *ON* are significantly better than the best aided pre-implant scores in the ear to be implanted (contralateral ear plugged)…
We have developed the TES program, which involves Targeted selection and Enhanced care, delivered on the basis of Stepped care (TES). The primary study aim is to evaluate the effectiveness of the TES-program compared to usual care in reducing…
Primary objectives:1.1 To investigate the differences between patients* and resident loved ones' perceptions of patients* health status and problematic ADLs.1.2 To study prospectively the effects of an acute COPD exacerbation on resident loved…
The main objective of the study is to gain insight into the cost-effectiveness of BPR compared to care as usual (CAU) for patients withSMI who have a wish for change in their societal participation. Research questions:1. Is BPR (cost-)effective…
Analyse costs and effects of point of care (POC) C-reactive protein (CRP) measurement in children with non-severe lower respiratory tract infection (LRTI) in primary care.
With the proposed study we aim to gain insight into the effects of oxytocin (OT) on both parents* and grandparents* sensitive, empathic, and protective responses to their (grand)children, and in the neural origins of these responses.The primary…
The primary study objective is to assess whether CML patients who respond to treatment with nilotinib (MMR within 12 months of treatment) differ from the non-responders in terms of adherence. Secondary objective is to evaluate whether responders and…
The aim of this study is to examine how many persons with burns experience problems in different social areas, and which factors prospectively impact on functioning. Predictors that will be investigated in this population relate to invalidation,…
Main: To assess the effect of an early extra measles immunization between 6and 12 months of age on the development of humoral and cell-mediatedimmunity against measles following routine MMR immunization at 14months of age.Secundary:Determine effect…
The primary aim of the study is to assess whether DWI, DCE-MRI, T2*, and 18F-HX4-PET/CT predict overall survival in patients with pancreatic cancer treated with surgery and adjuvant chemotherapy or with neoadjuvant radiochemotherapy, surgery and…
The main aim is to investigate clinical effects of different implementation methods of online supported self-management for COPD patients in primary care. Secondary objectives include effects on well-being, health care use and actual use of the…
The primary objective of this study is:to evaluate the effect of RPM + in-clinic follow-up versus in-clinic follow-up only on patient-reported health status/quality of life after implantation with an ICD/CRT-D device. The secondary objectives are: 1…
Primary objective;Confirm superiority of IgG antibody levels against pertussis toxin (Ptx), present in the acellular vaccines, in infants at the age of 3 months of mothers having received a pertussis vaccine during pregnancy versus infants of…
Primary Objective: The overall aim of this study is to develop a reliable and valid IADL questionnaire for use in brain tumor patients. Parallel versions of this questionnaire will be developed; a patient-based version and a proxy-based version.…
Investigate whether the "Smarter Pregnant" intervention in comparison with four screenings with food- and lifestyle advising leads to an improvement in unhealthy food habits (vegetables, fruit, folic acid use) after 24 weeks intervention,…