2570 results
The first aim is to investigate whether SIP indicators measured with VR are better predictors of aggression in real-life than SIP indicators measured with hypothetical vignettes in youth with MID-BIF. The second aim is to explore whether we can…
To determine the impact of prior BCG vaccination on the duration of immunogenicity of the BioNTech/Pfizer mRNA COVID*19 vaccine.
The primary objective of this study is to further discribe the natural course and clinical characteristic of infantile FSHD.The secondary objectives are: - To identify (epi)genetic and environmental disease modifying factors that contribute to…
The purpose of this study is to establish efficacy and safety of ligelizumab (QGE031) versus placebo in participants with chronic inducible urticaria who remain symptomatic despite treatment with H1 antihistamine.
The primary objective of this study is to establish molecular profiles in lower rectal biopsies as close to the internal fistula orifice tissue and fistula scrapings based on single cell RNA sequencing, cellular protein expression by CyTOF and…
The primary goal is to compare functional (language) areas in the brain found by preoperative fMRI, to those found during intraoperative ESM (electrical stimulation mapping) and fUS (functional ultrasound) during awake craniotomies, to see whether…
This study has been transitioned to CTIS with ID 2024-517846-32-00 check the CTIS register for the current data. To evaluate the effect of prolonged duration of (fos)aprepitant prophylaxis on the prevention of delayed CINV (complete remission in the…
To explore feasibility and efficacy of endoscopic unilateral drainage of patients with presumed perihilar cholangiocarcinoma eligible for major liver resection using a novel fully covered metal stent with a retrieval string.
Primary Objective:* The primary objective of this study is to determine the influence of different anatomical positions on step 2 of the PRAETORIAN score.Secondary Objective(s):* The influence of the different anatomical positions on the total…
Primary Objective: To evaluate potential changes in body composition and REE after NMES therapy at home for 12 weeks.We hypothesize that NMES therapy would result in hypertrophy of gluteal and hamstring muscles, and an increase in LL-LBM, total LBM…
To investigate the effects of hemarthrosis of the immune modulary properties of adipose stromal cells.
The primary objective is to determine if there is a difference in autonomic function between patients with Alzheimer*s disease (MCI and AD) and a matched control group. The secondary objectives will be explorative and aimed to investigate…
Our primary aim is to evaluate in clinical practice the predictive value of unruptured intracranial aneurysm wall enhancement for aneurysm growth. It will allow to set up a secure, efficient and personalized follow-up.
The aim of the study is to compare the CsA level in blood collected with a venipuncture with the CsA level in blood collected from the CVC during administration of CsA through the CVC. This to test the reliability of CsA levels in central venous…
Primary Objectives: - To determine the protective efficacy of repeated exposure to male Schistosoma mansoni (Sm) cercariae in healthy Schistosome-naïve volunteers based on CAA levels.- To determine the safety and tolerability of repeated exposure to…
The primary goal of this study is to compare ultrasound-guided ANB with FHB for analgesia during closed reposition of distal forearm fractures. Secondary goals are evaluation of feasibility in the ED regarding time and procedure success rate.…
This study aims to validate an integrated care model that is standardized and can easily be carried out in any other hospital.Primary objectiveThe primary objective is to determine the effect of a nurse-led, technology-supported, personalized care…
• To demonstrate the efficacy of ATR-002 versus placebo in addition to standard of care based on the clinical severity status in adult hospitalized patients with COVID-19• To show that ATR-002 in addition to standard of care shortens the time to…
Clinical Trial Protocol section 2.The main objectives of the trial are to assess the safety and tolerability of two doses of ABNCoV2, formulated with and without the adjuvant MF59, in healthy adult volunteers and to identify the dosage and…
The main objective of the study is to assess the albuminuria lowering effects of semaglutide 2.4 mg s.c. once weekly (Semaglutide 3 mg/ml) compared to placebo in obese/overweight non-diabetic individuals with elevated albuminuria.