1335 results
To study if there is a role for prophylactic VZV vaccination prior to transplantation to boost the patients B- and T-cell repertoire and thereby reducing the incidence and morbidity associated with herpes zoster.
The general objective of the intervention trial will be to evaluate the effect of this web-based behavioral intervention on psychological outcomes (i.e., anxiety and quality of life), physiological parameters (i.e., ventricular arrhythmias and…
This study will evaluate the antitumor activity of RAD001 versus placebo in patients with angiomyolipoma associated with either TSC or LAM.
(1) To asses the influence of P-gp function at the BBB on flumazenil binding to the GABAA-receptor in pharmacoresistant patients with temporal lobe epilepsy (TLE), using PET and [11C]flumazenil as a ligand and tariquidar as P-gp blocker. (2) If we…
· Explore the relative impacts of iodine concentration versus iodine delivery rate on intra-coronary attenuation. · Describe the effect of iodine concentration on contrast bolus characteristics e.g. bolus homogeneity, time-to-peak, and pressure…
ObjectiveTo investigate the performance of paclitaxel-coated balloon expandable stainless steel coronary stent for the treatment of infrapopliteal stenoses and occlusions in patients with critical limb ischemia compared to percutaneous transluminal…
Objectives:Medical: What is the effect of an exercise training program in children and young adults (up to 20 years of age) who have undergone treatment for ConHD (tetralogy of Fallot or Fontan procedure) on: a) aerobic fitness, b) ventricular size…
The purpose of the study is to evaluate the safety and effectiveness of the LINX device in the treatment of GERD
First, to estimate the cost-effectiveness of SCIT with tree pollen (TP), grass pollen (GP), and house dust mites (HDM) - the most prevalent allergies treated with SCIT - or combinations compared with UC. Second, to estimate the clinical efficacy of…
In the present proposal, we aim to answer whether antenatal allopurinol administration does reduce hypoxic-ischaemic encephalopathy in neonates exposed to intra-uterine asphyxia.
1. To evaluate efficacy of vorinostat in the treatment of patients with polycythaemia vera (PV) and essential thrombocythaemia (ET) 2. To evaluate if vorinostat as monotherapy of patients with PV and ET is followed by a decline in clonal…
This study exists of two parts:Cross-sectional study: what are the precise characteristics of physical functioning in EOD patients in comparison to a control group? Not all EOD patients show apathy and physical inactivity. It will be examined…
The primary objective of this pilot study is to assess the prevalence of visual field defects in formerly eclamptic women. The secondary objective is to compare the vision-related quality of life between formerly eclamptic and normotensive parous…
This study will evaluate the antitumor activity of RAD001 versus placebo in patients with subependymal giant cell astrocytomas (SEGA) associated with Tuberous Sclerosis Complex (TSC).
Primary question• Which bite size should be used to close a midline incision to prevent incisional hernia?Secondary questions• Is there a difference in postoperative complications between the two patient groups?• Is there a difference in…
The aim of this study is to determine safety, patency of placement and long term symptom-free outcome of a covered self expandable metal stent in patients with a benign CBD stricture.
•What is the prognostic value of CO2 reactivity compared to standard TCD measurements to predict the occurrence of DCI in patients with SAH?•Does magnesium therapy change CO2 reactivity after SAH?
The aim of the study is to quantify the accuracy and cost-effectiveness of a diagnostic decision rule for OBD, in patients with persisting lower gastro-intestinal complaints in primary care.
There is a double study objective:- First the effects of a PRP-injection in the treatment of the jumper's knee in comparison with the effects of a placebo injection - Second the effects of a PRP-injection in comparison with the effects of an…
The aim of this study is to determine the effects of fumarate therapy in combination with the H1-receptor blocker Cetirizine in psoriasis patients. Further to evaluate whether there is a decrease in the side effects of fumarate therapy during the…