1335 results
The key objectives of this study are:1. To determine by means of IENFD whether the PNS is involved in patients with autonomic complaints in MS. The obtained IENFD values will be compared with the age and gender matched healthy normative data,…
Comparing fertilty of male galactosemia patients to a control group
The study is a diagnostic study for the diagnostics of sarcoidosis, in where a new, endo-sonographic procedure is compared to the current, bronchoscopic method.The objective is to assess the accuracy, safety and patient tolerance of endo-sonography…
We want to investigate if in critically ill patients use of LMWH is associated with stable plasma levels of anti-Xa activity. Furthermore, we want to investigate if GFR and circulation influence anti-Xa activity and which complications can occur.…
Single dose:The objectives of Part 1 (single dose escalation part) are to examine the safety, tolerability and pharmacokinetics (i.e., the circulating levels of TMC558445 in your blood over time) of increasing single oral doses of TMC558445, with…
To apply a novel blood assay to 150 patients undergoing a radical prostatectomy in order to assess whether this test can accurately identify indolent cancers and thereby prevent unnecessary treatments. To increase the accuracy of the flow cytometric…
The aim o this study is to examine the cause(s) of large increases in weight after lung transplantation; the effect of daily physical activity, daily food intake and resting energy expenditure will be investigated in COPD and lung fibrosis lung…
To assess the effects of single dose of 100 mg (±) 3, 4-Methylenedioxymethamphetamine (MDMA, "ecstasy") and/ or a single dose of alcohol (0.5 %0) on simulated driving performance (in a controlled experimental design).To assess the effects…
The main objective is to optimalize the treatment of Moroccan and Turkish patients with depressive and/or anxiety disorders by increasing the cultural competence of the mental health workers who treat these patients. The mental health workers will…
The main objective of this study is to determine the prevalence of low BMD measured with dual-energy X-ray absorptiometry (DEXA) and quantitative ultrasonography (QUS) in Providentia (a residential care facility for persons with refractory epilepsy…
The aim of this study is twofold. Firstly, to investigate the test-retest reliability of the MSRS in stroke patients. And secondly, to study changes in MSRS score overtime in stroke patients in order to examine: a) the predictive value of the MSRS…
to evaluate progression of IMT in post-coarctectomy patients in 7 years follow up.
1) To test the feasibility of vaccinating pregnant women against B. pertussis in preventing B. pertussis infection in newborn babies.2) To test the safety of vaccinating pregnant women against B. pertussis in preventing B. pertussis infection in…
The primary goal is investigate the method to achieve the most effective clearance od midmoecules in the first 6 hours of HVHF.The secondary goal is to determine to wich proportion the clearance of midmolecules due to proteinprecipitation declines…
treatment outcome in OCD. Objective: The objective for this study is fourfold. First we will determine whether DCS addition to behavioural exposure therapy may enhance fear extinction and improve symptoms in OCD. Our hypothesis is that improvement…
Drug craving and impulsivity will be assessed with questionnaires, fMRI/EEG using cue-reactivity and impulsivity paradigms. Relapse will be assessed by checking urine samples every week.
To examine whether it is possible to combine the sensitivity of neuropsychological tasks with the efficiency of brief cognitive instruments.
1.To relate activity of the HPA axis to OCD symptoms and prefrontal brain abnormalities, using plasma ACTH and urine cortisol measures.2. To examine the role of nucleus accumbens activity on changes in endogenous glucose production, energy…
To demonstrate the superiority of indacaterol 150 µg o.d. in combination with tiotropium 18 µg o.d. versus tiotropium 18 µg o.d. with respect to standardized area under the curve (AUC) for forced expiratory volume in 1 second (FEV1) between 5 min *…
The primary objective of the study is to determine the rate of majorbleeding events in cancer subjects receiving extended treatment withdalteparin (> 6 months and up to 12 months) for prevention ofrecurrent symptomatic venous thromboembolism…