72 results
To evaluate cost effectiviness of the SENS-U (continuous ultrasonic bladder monitoring) in urotherapy for children with functional daytime urinary incontinence.
This strategy will result in a reduction reduce the incidence of major adverse cardiovascular events (MACE) defined as death or non-fatal myocardial infarction and appear more efficient than care as usual.
To assess the effect of adding a tapering decision aid on a dynamic flare prediction model to disease-activity-guided dose optimisation (DGDO) on the incidence of flares and medication use.
The main objective is to study the effect of the nutritional intervention versus the control product on white matter development (as assessed using tract based spatial statistics of fractional anisotropy) using a DTI scan at the corrected age of…
The aim of this study is to reduce the need for colectomy and its* associated morbidity and mortality in patients with high-risk pT1 or low-risk pT2 colon carcinoma after endoscopic polypectomy by performing a (robot-assisted) laparoscopic wedge…
To determine whether CDT in high-risk PE relative to systemic thrombolysis is:- more effective and safer in terms of a reduction of the composite endpoint on all-cause mortality and adverse events defined as treatment failure, major&…
To compare postamputation pain (phantom limb pain and residual limb pain) one year postoperatively in patients receiving a lower extremity amputation with standard neurectomy versus those who received targeted muscle reinnervation.
The objective of this pilot study is to assess whether transportation of the sample via a pneumatic tube system (PTS) has any detrimental effects on the recovery of presepsin levels, when compared to traditional hand-delivery. This research will be…
To assess the efficacy of the Tinnitus Implant System on tinnitus loudness in adults with moderate to severe chronic tinnitus accompanied by normal hearing to moderately severe hearing loss at 6 months post-activation of the Tinnitus Implant System…
Feasibility of exergaming to reduce sedentary time in persons with an LVAD: The Heart-eXg LVAD-study
To determine the feasibility of tailored exergaming for persons with a LVAD (acceptability, the demand, the implementation, practicality, adaption, expansion, and perform limited-efficacy testing).
The primary objective of this study is to evaluate the diagnostic accuracy of physical examination and ultrasound to identify active synovial proliferation in haemophilia patients with subclinical synovial proliferation. The secondary…
Primary objective: study the technical feasibility and safety to perform stereotactic radiotherapy on MR-linac for cT1-2 glottic cancer patients.Secondary objectives: monitor the patient safety, toxicity and tolerability of this…
The objective of the proposed study is to assess the effect of a combined lifestyle intervention for patients with cancer, who suffer from the consequences of cancer and its treatment, on Health-Related Quality of Life (HRQoL)
To utilize the therascreen KRAS RGQ PCR Kit (KRAS Kit) as a screening test to identify KRAS G12C mutations in newly diagnosed metastatic NSCLC participants and thereby determine eligibility for enrolment into the Phase 3 clinical study (MK-1084-004…
The purpose of the pivotal study is to determine the safety and efficacy of IMPEDE-FX RapidFill for increasing the percentage of subjects with shrinkage of the abdominal aortic aneurysm sac when used as an adjunct to on-label EVAR stent graft…
The main objective of the SOPI study is to select the HRD test that best predicts longest PFS on PARP-i in non-BRCA1/2 EOC patients, in order to adequately select patients that will benefit from a PARP-i. Secondary objectives are: to…
To utilize the therascreen KRAS RGQ PCR Kit, as a screening test in Amgen*s Phase 3 Clinical Study Protocol 20210081, in order to identify patients with mCRC KRAS G12C mutation positive tumors to be enrolled in the drug clinical trial. Results of…
This study aims to determine the effect of real-time symptom monitoring on HRQoL in patients with mBC who start first-line chemo(immune)therapy. Further objectives include analyzing the effect of PRS monitoring on physical functioning, the severity…
Primary objective of this clinical investigation is to evaluate superiority of the signal quality of SOFT ECoG flexible high-density electrode grids compared to regular high-density electrode grids, routinely used at the UMC Utrecht. The signal…
The aim of this research is to decrease the number of involved margins, resulting in less adjuvant therapy and less local recurrences.