19 results on atopic dermatitis
The goal of this study is to evaluate the effect of Gladskin on usage of topical corticosteroids in patients with atopic dermatitis. Secondary goals are to retrieve information about the effect of Gladskin on clinical symptoms, quality of life,…
To evaluate the safety and efficacy of multiple doses of ABT-494 (Upadacitinib) monotherapy versus placebo in the treatment of adults with moderate to severe atopic dermatitis.
Primary Objective- To assess efficacy and pharmacodynamic effects of topical omiganan BID Secondary Objectives- To assess safety and tolerability of topical omiganan BID
To address the hypothesis that a potato derived protease inhibitor cream significantly limits perianal dermatitis in patients after colorectal surgery.
Determine the relationship between stratum corneum lipids (and their enzymes) and inflammatory markers in patients with AE. This is achieved by measuring:i) The SC lipid matrix and bound lipids, focussing on ceramides and its biosynthesis (i.e. the…
The primary objective of this study is to evaluate whether the recovery of the skin barrier after acute perturbation by repetitive application of adhesive tape (*tape stripping*) is accelerated following irradiation with visible light. The secondary…
The main objective is to evaluate the cytokine response to histamine iontophoresis in vivo, dynamically and non-invasively by means of transdermal analysis patches. The secondary objective is to correlate the cytokine response with morphological…
Primary objective:Assess the safety and efficacy of adalimumab prior to surgery in subjects with moderate to severe HS who are surgical candidates.Secondary objectives:Assess the impact of adalimumab on the planned HS surgical site before surgery,…
prebiotics and fatty acids will decrease the burden of recurrent respiratory infections in children
To evaluate whether YCF with added scGOS/lcFOS and n-3 LCPFUAs can decrease the number of upper respiratory tract infections compared to cow*s milk in children aged 12-36 months with recurrent upper respiratory tract infections.
To compare the efficacy of alitretinoin and cyclosporine in the treatment of hand eczema.
Primary:To determine the prevalence of pruritis in patients with hidradenitis suppurativa.Secondary:- to evaluate pruritis severity and its effect on three elements of daily activities;- to evaluate differences in extensiveness of HS in relation to…
The primary objectives are to investigate attentional interference by somatosensory itch and pain stimuli in healthy subjects, both on a behavioural (SAT) level and a neurophysiological level (EEG alpha-desynchronization).Secondary objectives…
Primary Objective: To assess the anti-neoplastic activity of flotetuzumab in patients with PIF/ER AML, as determined by the proportion of patients who achieve CR/CRhSecondary Objectives:To describe response rate, duration of response, event-free…
Primary Objectives* To explore the pharmacodynamic effects of topically applied omiganan in patients with external genital warts* To explore clinical efficacy of omiganan compared to placebo in patients with external genital warts.Secondary…
Primary ObjectiveTo explore the pharmacodynamics effects of topically applied OMN ono Tape-stripped skin of healthy volunteerso Tape-stripped and IMQ-primed skin of healthy volunteerso Tape-stripped skin prior to IMQ applicationSecondary Objectives…
Primary objective- To explore the pharmacodynamic effects of topically applied IMQ (in combination with or without TS) - To identify dose-response relationship of topically applied IMQ Secondary objective- To assess safety and tolerability of…
The aim of this study is to investigate alterations in brain activity in UF patients by detecting and characterizing MEG changes, using network theory.