33 results on atopic dermatitis
Primary ObjectiveTo evaluate the safety and tolerability of topical XZ.700 in patients with mild to moderate atopic dermatitisSecondary ObjectivesTo investigate the PD effects of XZ.700 in patients with mild to moderate atopic dermatitis To evaluate…
The primary objective is to assess the long-term safety of nemolizumab (CD14152) in adult and adolescent subjects with moderate-to-severe atopic dermatitis (AD).The secondary objective is to assess the long-term efficacy of nemolizumab (CD14152) in…
Primary objective: The primary objective is to assess the efficacy and safety of nemolizumab (CD14152) after a 16-week treatment period in adult and adolescent subjects with moderate-to-severe atopic dermatitis (AD) not adequately controlled with…
Primary:To compare the efficacy of abrocitinib 200 mg once daily (QD) versus dupilumab (as per label guidelines) in adult participants on background topical therapy with moderate to severe atopic dermatitis (AD).Key SecondaryTo compare the efficacy…
Primary Objective To evaluate the safety and tolerability of topical XZ.700 in patients with mild to moderate atopic dermatitis Secondary Objectives To investigate the PD effects of XZ.700 in patients with mild to moderate atopic dermatitis To…
To assess long-term safety, tolerability and efficacy of upadacitinib in adult subjects with moderate to severe atopic dermatitis who successfully completed treatment in the M16-046 study. Efficacy will be evaluated through Week 52, and safety and…
Primary Objective: 1.1 Does treatment according to the Dutch EMDR protocol for Urge reduce scratching behavior in AD patients? Hypothesis:1.1 H1: Treatment according to the Dutch EMDR protocol for Body Focused Repetitive Behavior , version…
The precise mechanisms driving onset and course are insufficiently understood, disease progression from a current patient state and/or the development of comorbidities are unpredictable, and the optimal type and time-point for intervention is as yet…
Determine the frequency, phenotype and function of disorder-related immune cells, or levels of immune molecules in skin and peripheral blood of patients with inflammatory skin diseases, during the active phase of disease prior to and/or at any time…
This is a set-up for a challenge pruritus model. We expect to initiate a local, reversible itch- response
Main study:To evaluate the efficacy of dupilumab in patients with inflammatory subtypes of severe chronic hand eczema with an inadequate response or intolerance to alitretinoin and in patients with concomitant positive patch test results.Substudy:…
Primary Objectives- To evaluate disease related characteristics in patients with different vulvar conditions compared to healthy volunteers - To evaluate the variability of the selected biomarkers between subjects, and within subjects over time.…
The objectives of this follow-up study of the EPITOPE study are:• To assess the clinical benefit of Viaskin Peanut after up to 3 years of epicutaneous immunotherapy (EPIT) to induce/maintain desensitization to peanut in peanut-allergic children;• To…
PrimaryTo evaluate the long-term safety and tolerability of baricitinib in patients with SLE.
- The purpose of this study is to evaluate the efficacy of the study drug to lung function, exacerbations and quality of life with patients with COPD. The safety and tolerability of the study drug is monitored as part of this study.
The primary objective is to assess the long-term safety of nemolizumab (CD14152) insubjects with prurigo nodularis (PN).The secondary objective is to assess the long-term efficacy of nemolizumab (CD14152)in subjects with PN
The primary objective is to assess the efficacy of nemolizumab (CD14152) compared to placebo in subjects >= 18 years of age with prurigo nodularis (PN) after a 16-week treatment period.
To evaluate the efficacy based on the histological response
Primary objective: to identify predicting phenotypical and endotypical biomarkers for the response to dupilumab in adult patients with CRSwNP, by comparing the type 2 inflammation in the peripheral blood and nasal polyp tissue at baseline and after…
Primary ObjectiveThe primary objective of the study is to determine the effect of ND0612 on daily *ON* time without troublesome dyskinesia (defined as the sum of "ON" time without dyskinesia and *ON* time with non-troublesome dyskinesia)…