No registrations found.
ID
Source
Brief title
Health condition
Carbon monoxide, compound A, Anesthesia, Carbon dioxide absorbents, Desiccation. Koolmonoxide, Anesthesie, Kooldioxide absorbers, Uitdroging.
Sponsors and support
Intervention
Outcome measures
Primary outcome
Amount of carbon monoxide or compound A produced.
Secondary outcome
N/A
Background summary
All modern vapor anesthetics are capable of carbon monoxide (CO) production as a result of interaction with desiccated strong base containing carbon dioxide absorbents. In desiccated absorbents, desflurane produces the highest concentrations of CO. Sevoflurane is known to produce the nephrotoxic compound A (CA) independent of the water content of the carbon dioxide absorbent. The purpose of this study is to register the average CO concentrations in forty patients receiving desflurane or sevoflurane anesthesia after implementation of a safety protocol adapted from Woehlck et al., developed to prevent desiccation of the strong base containing absorbent Drägersorb 800 Plus® while still maintaining the possibility of flushing the ventilating circuits of the anesthesia machines with a flow of air.
Study objective
The purpose of this study is to register the average CO concentrations in forty patients receiving desflurane or sevoflurane anesthesia after implementation of a safety protocol to prevent desiccation of the strong base containing absorbent Drägersorb 800 Plus®.
Study design
N/A
Intervention
Desflurane or sevoflurane anesthesia.
Inclusion criteria
1. Non-smoking patients;
2. American Society of Anesthesiologists physical status class 1 to 3
scheduled for a surgical procedure that would last at least ninety minutes.
Exclusion criteria
1. Younger than 18 years of age;
2. Suffering from terminal renal failure.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL955 |
| NTR-old | NTR981 |
| Other | : |
| ISRCTN | ISRCTN84188372 |