No registrations found.
ID
Source
Brief title
Health condition
Tinnitus, fMRI, 7T, subcortical, auditory
oorsuizen, fMRI, 7T, subcorticaal, auditief
Sponsors and support
Intervention
Outcome measures
Primary outcome
The main study endpoint will be the tonotopic map in auditory brainstem structures including the cochlear nucleus complex up to the inferior colliculus.
Secondary outcome
1. fMRI activity in auditory brainstem structures;
2. Structural (volumetric) measurements in auditory brainstem structures.
Background summary
The present study is a pilot study in ultra-high field fMRI of subcortical auditory structures in patients with tinnitus.
Study objective
The underlying mechanism of tinnitus is tonotopic reorganisation of subcortical auditory areas.
Study design
N/A
Intervention
N/A
Postbus 5800
R.A.G.J. Arts
Maastricht 6202 AZ
The Netherlands
+31 (0)43 3881184
remo.arts@mumc.nl
Postbus 5800
R.A.G.J. Arts
Maastricht 6202 AZ
The Netherlands
+31 (0)43 3881184
remo.arts@mumc.nl
Inclusion criteria
The main inclusion criterion of the tinnitus group is pure tone-, unilateral-, chronic- and subjective tinnitus which is longer present than 6 months. Age ≥ 18 years.
Exclusion criteria
Exclusion criteria are: Fletcher Index > 50 dB HL for both ears, difference in average hearing threshold of more than 10 dB between left and right ear, hyperacusis, phonophobia, misophonia, neurological-, neurosurgical- and psychiatric history, use of dopaminergic drugs since this medication greatly influence the fMRI scans, current treatment of tinnitus and implanted devices or other metal objects that are not suitable for MRI.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL3797 |
| NTR-old | NTR3970 |
| Other | NL44760.068.13 : 44760 ABR |
| ISRCTN | ISRCTN wordt niet meer aangevraagd |