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ID
Source
Brief title
Health condition
Stroke
Sponsors and support
Intervention
Outcome measures
Primary outcome
Knee flexion during gait
Secondary outcome
Kinetics and kinematics of the ankle, knee, hip and pelvis and BORG and VAS questionnaires on knee stability.
Background summary
The current treatment of stiff knee gait, that focusses at the main causes namely over activity of the m. rectus femoris, is not effective in all patients with a CVA (Cerebro Vascular Accident). Literature also describes over activity of the m. vastii as a cause of stiff knee gait. Chemodenervation can be used to reduce muscle over activity. The efficiency of treatment in patients with stiff knee gait could be increased by chemodernervation of the m. vastus intermedius and the m. rectus femoris. The study is searching for the effect of lidocaine injections in both muscles on the gait pattern.
Objective of the study: Determining the effect of chemodenervation by lidocaine of the m. vastus intermedius and the m. rectus femoris in stroke patients presenting a stiff knee gait.
Study design: Before-after design with no control group.
Study population: 18 subjects with a CVA presenting with stiff knee gait.
Intervention: lidocaïne injections in the m. vastus intermedius and the m. rectus femoris.
Primary study outcome: Knee flexion during gait
Secundary study outcomes: Kinetics and kinematics of the ankle, knee, hip and pelvis (VICON, EMG) and questionnaires (BORG,VAS) on knee stability.
Study objective
Chemodenervation by lidocaine of the m. vastus intermedius and the m. rectus femoris improves gait pattern in stroke patients presenting a stiff knee gait.
Study design
None
Intervention
Chemodenervation by lidocaine of the m. vastus intermedius and the m. rectus femoris
Inclusion criteria
Age > 18 - Stroke occurred over 6 months ago - patient presents stiff knee gait - patient able to walk independently (Functional Ambulation Categories score (FAC) ≥3) - over activity of the m. vastus intermedius and m. rectus femoris - Patient is orientated in time, place and person and is able to understand and follow instructions
Exclusion criteria
Existing pathologies or problems that are not caused by a CVA, that are of influence on the gait pattern - Allergy to lidocaine or other elements found in lidocaine hydrochloride - inflammation in the injection area
Design
Recruitment
IPD sharing statement
Followed up by the following (possibly more current) registration
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Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL8018 |
| Other | MEC TWENTE : P19-04 |